DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rrp42 and Exosc7

DIOPT Version :9

Sequence 1:	NP_725517.2	Gene:	Rrp42 / 36766	FlyBaseID:	FBgn0034065	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001094195.1	Gene:	Exosc7 / 316098	RGDID:	1309758	Length:	291	Species:	Rattus norvegicus

Alignment Length:	295	Identity:	144/295 - (48%)
Similarity:	202/295 - (68%)	Gaps:	5/295 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAYVALSEAEKTYILHGVEDDFRCDGRSRRDYRPMDLETGLVSNASGSARLRLANTDILVGVKTE 65
            ||.|:||||||.||:|||::|.|.|||...|||.:::||.:|||.|||||::|.:||||||||.|
  Rat     1 MASVSLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAE 65

  Fly    66 IDVPNPLTPEFGKLEFFVDCSANATPEFEGRGGSDLAQELILSLQNAYESPLAFNYRTLCLIPGQ 130
            :..|....|..|.||||||||||||||||||||.||..|:..:|...:.:..:.:.|:||:.|.:
  Rat    66 MGTPKLERPSEGYLEFFVDCSANATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLRSLCISPRE 130

  Fly   131 QCWKLYIDILILECGGNLHDAVSLAAKAALFNTKLPRVTATMLDAGITDLIISDNPYDCTRIGIE 195
            .||.||:|:|:|||||||.||:|:|.|||||||::|||.....:.|..|:.:||:||||.|:.:|
  Rat   131 HCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVE 195

  Fly   196 TVPLLVTVCKIGDYVLVDPSAEEEVCSTVSMVVSVSMRNGQAFLSGTHLTGGGAMHRDTMRNCLE 260
            .||.:||:||||...:||.:.:||.||..|::|||:   .:..::.....|.|::..:::...:|
  Rat   196 NVPCIVTLCKIGCRHVVDATLQEEACSLASLLVSVT---SKGVVTCMRKVGKGSLDPESIFEMME 257

  Fly   261 LGLAIGEHLDRLLTKMLNLEQQRVGLKRPQIVGFL 295
            ....:|:.|...|..:|:.|:. :|.|||: ||||
  Rat   258 SSKRVGKVLHMSLQSLLHKEES-LGPKRPK-VGFL 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rrp42	NP_725517.2	RNase_PH_RRP42	5..278	CDD:206772	131/272 (48%)
Rrp42	NP_725517.2	Rrp42	6..277	CDD:225034	131/270 (49%)
Exosc7	NP_001094195.1	Rrp42	1..273	CDD:225034	134/274 (49%)
Exosc7	NP_001094195.1	RNase_PH_RRP42	5..276	CDD:206772	132/273 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354242
Domainoid	1	1.000	168	1.000	Domainoid score	I3745
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8994
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2811
OMA	1	1.010	-	-		QHG54644
OrthoDB	1	1.010	-	-		D447176at33208
OrthoFinder	1	1.000	-	-		FOG0001408
OrthoInspector	1	1.000	-	-		oto97539
orthoMCL	1	0.900	-	-		OOG6_103422
Panther	1	1.100	-	-	LDO	PTHR11097
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6099
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910