DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rrp42 and Exosc9

DIOPT Version :9

Sequence 1:	NP_725517.2	Gene:	Rrp42 / 36766	FlyBaseID:	FBgn0034065	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001020577.1	Gene:	Exosc9 / 294975	RGDID:	1307888	Length:	437	Species:	Rattus norvegicus

Alignment Length:	285	Identity:	76/285 - (26%)
Similarity:	133/285 - (46%)	Gaps:	14/285 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAYVALSEAEKTYILHGVEDDFRCDGRSRRDYRPMDLETGLVSNASGSARLRLANTDILVGVKTE 65
            |....||..|:.::|..:|:..|.|||...|||.:.:..|   ...|...:.|..|.:|..|..|
  Rat     1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCE 62

  Fly    66 IDVPNPLTPEFGKLEFFVDCSANATPEFEGRGGSDLAQELILSLQNAYESPLAFNYRTLCLIPGQ 130
            :..|.......|.|.|.::.|..|.|.||....|||..:|...|:....:....:..:||::.|:
  Rat    63 LVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLLERCLRNSKCIDTESLCVVAGE 127

  Fly   131 QCWKLYIDILILECGGNLHDAVSLAAKAALFNTKLPRVTATMLDAGITDLIISDNPYDCTRIGIE 195
            :.|::.:|:.:|...||:.||.|:||..||.:.:.|.|:.    .|....:.:....|...:.|.
  Rat   128 KVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSV----QGEEVTLYTPEERDPVPLSIH 188

  Fly   196 TVPLLVTVC--KIGDYVLVDPSAEEEVCSTVSMVVSVSMRNGQAFLSGTHLTGGGAMHRDTMRNC 258
            .:|:.|:..  :.|.|:||||:..||......:|:::   |....:.....:||..:.:|.:..|
  Rat   189 HMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAM---NKHREICTIQSSGGIMLLKDQVFRC 250

  Fly   259 LEL-GLAIGEHLDRLLTKMLNLEQQ 282
            .:: |:.:.| :..|:.|.|..:|:
  Rat   251 SKIAGVKVAE-ITELIQKALENDQR 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rrp42	NP_725517.2	RNase_PH_RRP42	5..278	CDD:206772	73/275 (27%)
Rrp42	NP_725517.2	Rrp42	6..277	CDD:225034	73/273 (27%)
Exosc9	NP_001020577.1	RNase_PH_RRP45	6..264	CDD:206773	71/268 (26%)
Exosc9	NP_001020577.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	339..437
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810