Protein Alignment Rrp42 and EXOSC8

DIOPT Version :9

• Sequence 1: NP_725517.2
• Gene: Rrp42 / 36766
• FlyBaseID: FBgn0034065
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: XP_006719826.1
• Gene: EXOSC8 / 11340
• HGNCID: 17035
• Length: 313
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 68/260 - (26%)
• Similarity: 125/260 - (48%)
• Gaps: 9/260 - (3%)

  Fly    19 EDDFRCDGRSRRDYRPMDLETGLVSNASGSARLRLANTDILVGVKTEIDVPNPLTPEFGKLEFFV 83
            :::.|.|||...::|...:..|.:|.|.|||.::|.||.::.|||.|...|:...|:.|.:...|
Human    56 KENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPDKGYVVPNV 120

  Fly    84 DCSANATPEFEGRGGSDLAQELILSLQNAYESPLAFNYRTLCLIPGQQCWKLYIDILILECGGNL 148
            |.....:..|......:.||.....:.:..|:........||:.||:..|.||.|::.|:..||:
Human   121 DLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVLYCDLICLDYDGNI 185

  Fly   149 HDAVSLAAKAALFNTKLPRVTATMLDAGITDLIISDNPYDCTRIGIETVPLLVTVCKIGDYVL-V 212
            .||.:.|..|||.|.:||.||... :..:.::.:....|    :.|.|.|:..:.....|.:| |
Human   186 LDACTFALLAALKNVQLPEVTINE-ETALAEVNLKKKSY----LNIRTHPVATSFAVFDDTLLIV 245

  Fly   213 DPSAEEEVCSTVSMVVSVSMRNGQAFLSGTHLTGGGAMHRDTMRNCLELGLAIGEHLDRLLTKML 277
            ||:.|||..:|.::.:   :.:.:..|...|..||..:....:::|:...:...:.:.:|:.:::
Human   246 DPTGEEEHLATGTLTI---VMDEEGKLCCLHKPGGSGLTGAKLQDCMSRAVTRHKEVKKLMDEVI 307

  Fly   278  277
            Human   308  307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rrp42	NP_725517.2	RNase_PH_RRP42	5..278	CDD:206772	68/260 (26%)
		Rrp42	6..277	CDD:225034	68/258 (26%)
EXOSC8	XP_006719826.1	RNase_PH_RRP43	56..303	CDD:206774	67/254 (26%)
		PRK04282	60..309	CDD:235268	68/256 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D447176at33208
OrthoFinder	1	1.000	-	-		FOG0001408
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820