Protein Alignment CG8389 and SLC16A3

DIOPT Version :10

• Sequence 1: NP_611076.2
• Gene: CG8389 / 36764
• FlyBaseID: FBgn0034063
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_004198.1
• Gene: SLC16A3 / 9123
• HGNCID: 10924
• Length: 465
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 80/391 - (20%)
• Similarity: 137/391 - (35%)
• Gaps: 115/391 - (29%)

  Fly   203 KNIYGFEQFLKENHRSELPEIDCHKTAILPYSSGTTGLPKGVELSHYNLVANLAQGSHPAISKYY 267
            |:||.::.     .:|.:...:...:|:.|....|:..|..:..|:::.|...:.|:...::...
Human   323 KSIYEYQP-----GKSSVLTNEKMSSAVSPTPDITSEPPGYIYSSNFHAVKRESDGTPGGLASLE 382

  Fly   268 QPEYLEKKETIL---TIPPFFHIYGLNGILHMVLKSKNHVVSIPR-FIPEDYIQCLAEF------ 322
            ....:.|  ::|   .||    :.||:|:......:.......|| |||.||::...||
Human   383 NERQIYK--SVLEGGDIP----LQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRRHD 441

  Fly   323 -------RPQFLFVVPSLLLFLATHPKVTPDLLSSVDSVLVGAAPASLQLQEKFKNKVGRDIDIA 380
                   |.:|.|...:|                           ..|.||:.....:.|.||
Human   442 DKEMRPARAKFDFKAQTL---------------------------KELPLQKGDVVYIYRQID-- 477

  Fly   381 QGYGMTESSPVTLCTPHRYDLSKVGTCGQLYPNTEAKIVSLSDGS---NLGPHQTGELYLRGPQI 442
            |.:               |:....|..| ::|.|..:::..::.:   .|.|.|..|.   |..|
Human   478 QNW---------------YEGEHHGRVG-IFPRTYIELLPPAEKAQPRKLAPVQVLEY---GEAI 523

  Fly   443 MKGYLNNET--------ATRETLVEDGYLRTGDVAYYD-------KEGFFFI--VDRTKE-LIKV 489
            .|...|.:|        ..|.||     ||..|..:|:       ::|.|.|  ||..|. |:|.
Human   524 AKFNFNGDTQVEMSFRKGERITL-----LRQVDENWYEGRIPGTSRQGIFPITYVDVLKRPLVKT 583

  Fly   490 KGNQV------SPTELENIILELPEVSDVAVAGVPDETAGELP----RAFVVVKPGSQLDEREVQ 544
            ..:.:      ||:....:..:.|:.....|  .||.:...|.    :|.....|.:. ||.|::
Human   584 PVDYIDLPYSSSPSRSATVSPQQPQAQQRRV--TPDRSQPSLDLCSYQALYSYVPQND-DELELR 645

  Fly   545 D 545
            |
Human   646 D 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS_MCT_SLC16	15..440	CDD:340910	47/256 (18%)
SLC16A3	NP_004198.1	MFS_MCT3_4	21..406	CDD:340988	18/93 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..438		9/18 (50%)
		Basolateral sorting signal. /evidence=ECO:0000269|PubMed:21199217	423..441		7/17 (41%)
		Basolateral sorting signal. /evidence=ECO:0000269|PubMed:21199217	441..465		5/50 (10%)