Protein Alignment CG8389 and SLC16A3

DIOPT Version :9

• Sequence 1: NP_611076.2
• Gene: CG8389 / 36764
• FlyBaseID: FBgn0034063
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001035887.1
• Gene: SLC16A3 / 9123
• HGNCID: 10924
• Length: 465
• Species: Homo sapiens
• Alignment Length: 481
• Identity: 111/481 - (23%)
• Similarity: 184/481 - (38%)
• Gaps: 86/481 - (17%)

  Fly    10 PDGGYGWIVVAAVALINMTNQSI---LSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLF 71
            ||||:||.|:....:|...:.:.   :|||.:..:.|......||   |.|:::....|..:|..
Human    16 PDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT---AWISSILLAMLYGTGPL 77

  Fly    72 IGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGL-ISPSTFMAINSYF 135
            ....:..|..|.|...|.:..:||:...:|........|......|.||.| ..||..| :|.||
Human    78 CSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIM-LNRYF 141

  Fly   136 TTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLNPPAKH 200
            :.:|..|.|::.||:.:....:..|.:.|.|.:|:|...|.:..|.|.....||.::||
Human   142 SKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPL------ 200

  Fly   201 NNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDLELLKDLVFW 265
                   ::|...|.                   .||       |..:||   :||.:.:|..|
Human   201 -------VVTAQPGS-------------------GPP-------RPSRRL---LDLSVFRDRGF- 228

  Fly   266 SIIVGMALVYTATINFTMIFPGFLGQTAQ---LNSQMVAFCMSLVAGADIVFRLLLPIVTDHLRI 327
               |..|:..:..:....:.|.|:...|:   :.....||.::::...||..|.....|....::
Human   229 ---VLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKV 290

  Fly   328 -PYRV------VFLIGIVGLFVARCVLAENQTLPVI-ITMSVLTGMMKSATVINNNLTISAHCRS 384
             ||.|      :|..|:..|  |.....:...|.|. |...:..||:.:.........:..|
Human   291 RPYSVYLFSFSMFFNGLADL--AGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTH--- 350

  Fly   385 EKLAGGLGLSMMSKGVIVI----TVGQLLGWVRDYADSYLICLYAQGVILLVVVLVWTPEILYRH 445
             |.:..:||.::.:.|.|:    :.|:||       |:..:.:|   |.:|....|.|..::...
Human   351 -KFSSAIGLVLLMEAVAVLVGPPSGGKLL-------DATHVYMY---VFILAGAEVLTSSLILLL 404

  Fly   446 RRQRCATNKSMETQ-SIDAAEVAKLN 470
            ....|...|..|.| .:.|||..||:
Human   405 GNFFCIRKKPKEPQPEVAAAEEEKLH 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	90/424 (21%)
		MFS_1	19..400	CDD:284993	84/395 (21%)
SLC16A3	NP_001035887.1	2A0111	8..444	CDD:331689	111/481 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..438		5/12 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020