DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and slc16a5b

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	XP_001919658.1	Gene:	slc16a5b / 794371	ZFINID:	ZDB-GENE-131120-181	Length:	547	Species:	Danio rerio

Alignment Length:	482	Identity:	106/482 - (21%)
Similarity:	191/482 - (39%)	Gaps:	54/482 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SSRVVPDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQK-MQEDTFTAALITNLNSLALNFS 68
            ::::.||||:||:||||..|:.....:..|..| :|..|||. .|......:.:..:....|:..
Zfish    66 NAQLAPDGGWGWVVVAATILVLAMTLAFPSCIG-IFYTELQSDFQASNTETSWVPAIMMAVLHAC 129

  Fly    69 GLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINS 133
            |......::....|.....|.||..||:|..:||.......:......|.|..|....:...:..
Zfish   130 GPICSVLVERCGCRATIIIGGILSGLGMAASSFAQTMVELYITAGIITGMGFSLCFQPSITMVGH 194

  Fly   134 YFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLNPPA 198
            ||..:|..|..:|..|..||..::|.|..|||.|.|:|.:.|.:..:.|......|.::||....
Zfish   195 YFVRRRAFANALSSTGTALGLSILPLLANYLLRNFGWRGSFLVLGGVLLNCCVCGAVMRPLAAKP 259

  Fly   199 KHNNRKHIRLLTEADGE--KTSPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDLELLKD 261
            |...|     ..|.|..  ||:.|.|     :|....|....:.|:.:.:.:.:  |.|| |..:
Zfish   260 KTETR-----TKETDNHHLKTNCLSV-----HQGLKGRLRATLSTIMTFLRRHM--AFDL-LCSN 311

  Fly   262 LVFWSIIVG---MALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIVTD 323
            ..|.:..:|   |.|.:...:.:.:.:....|    :.....|..|:::...:|:.|....||
Zfish   312 PYFCAYALGVSWMMLGFVVPLVYLVPYATAYG----MEQDQAALLMAILGLINIIVRPATAIV-- 370

  Fly   324 HLRIP-------YRVVFLIGIVGLFVARCVLAENQTLPVIITMSVLTGMMKSA------TVINNN 375
             ..:|       :..:|.|.:|...::.||.....:..|::...:|.|...|.      ||:.:.
Zfish   371 -FGLPRFRGSHNFAYLFAIAVVINGLSNCVCGIGTSFLVLLVYVILFGFSMSLVGSLLFTVLMDT 434

  Fly   376 LTISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVRDYADSYLICLYAQGV------ILLVVV 434
            :.:|      :....|||..:.:.::::....|.|.:.|....|:...:|..|      :.:::.
Zfish   435 VEMS------RFPSALGLISIMESIMLLLGPPLAGILVDSTGQYIYVFFACSVTGSTAGLFIMLS 493

  Fly   435 LVWTPEILYRHRRQRCATNKSMETQSI 461
            ..|...  .|.|.|..:::...:..|:
Zfish   494 FYWLDR--RRDREQVKSSSAHQDPHSL 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	92/424 (22%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	88/399 (22%)
slc16a5b	XP_001919658.1	2A0111	71..511	CDD:331689	105/468 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020