DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and Slc16a9

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	XP_038955085.1	Gene:	Slc16a9 / 687808	RGDID:	1596295	Length:	508	Species:	Rattus norvegicus

Alignment Length:	525	Identity:	118/525 - (22%)
Similarity:	200/525 - (38%)	Gaps:	129/525 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDVQSSRVVPDGGYGWIVVAAVALINMTNQSILSVFGQ-------LFVGELQKMQEDTF------ 52
            |..|.|   ||||:||::|            ::|.|.|       |.||.|.....|.|
  Rat     1 MGFQKS---PDGGWGWVIV------------VVSFFTQFLCYGSPLAVGVLYVEWLDAFGEGKGK 50

  Fly    53 ---TAALITNLNSLALNFSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSF 114
               ..:|.:.:..||.....||    :.||..|.|......|||.||.|.:.|...:.....|..
  Rat    51 TAWVGSLASGVGLLASPVCSLF----VSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGI 111

  Fly   115 FVGFGLGLISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSS 179
            .||.|.||:..:|......||.::||.|:|:...|:.:|..:...|.|.|::.:|....:|.:.:
  Rat   112 VVGLGCGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGA 176

  Fly   180 LSLFGLFGAAFLKPL--------------NPPAKHN--NRKHIRLLTEADGEKTSPLQVVIVPTN 228
            |:|..|...:.::||              |.|.:::  |.|      |.:.|:|...|    ...
  Rat   177 LALNILACGSLMRPLQTSDCPFPEKIAPENVPDRYSIYNEK------EKNQEETMTFQ----DKG 231

  Fly   229 QSKIERSPPNVD-------------------------------TLCSRMGQRLVQAM------DL 256
            .|..::..||.|                               ..|.::.:|..|..      ..
  Rat   232 YSNEDKCLPNGDWGRETSLPKNPTGAAHTKEPEPYKKKVVEQTNFCKQLAKRKWQVYRNYCGETA 296

  Fly   257 ELLKDLVFWSIIVGMALV----YTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLL 317
            .|.|:.||.::.|.:.|.    :..::....:...:..:...|...:::....:.|    |.:||
  Rat   297 SLFKNKVFSALFVAILLFDIGGFPPSLLMEDVARSYHVREEDLTIPLISIFGIMTA----VGKLL 357

  Fly   318 LPIVTDH--LRIPYRVVFLIGIVGLFVARCVLAENQTLPVIITMSVLTGMMKSATVINNNLTISA 380
            |.|:.|.  :...|..|..:.|.||.:....||::     .:|:::|:|::...|   .|.:|..
  Rat   358 LGILADFKWVNTLYLYVATLIITGLALCAIPLAKS-----YVTLAILSGILGFLT---GNWSIFP 414

  Fly   381 HCRS-----EKLAGGLGLSMMSKGVIVITVGQLLGWVRDYADSYLICLYAQG--------VILLV 432
            :..:     :|||...|:.|...|:.......::||..|:..:|.|..|..|        ::||.
  Rat   415 YVTTKTVGIDKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLLA 479

  Fly   433 VVLVW 437
            ::..|
  Rat   480 ILPCW 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	104/485 (21%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	98/460 (21%)
Slc16a9	XP_038955085.1	MFS_MCT9	12..479	CDD:340986	109/504 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920