Protein Alignment CG8389 and SLC16A2

DIOPT Version :10

• Sequence 1: NP_611076.2
• Gene: CG8389 / 36764
• FlyBaseID: FBgn0034063
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_006508.2
• Gene: SLC16A2 / 6567
• HGNCID: 10923
• Length: 539
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 103/488 - (21%)
• Similarity: 177/488 - (36%)
• Gaps: 106/488 - (21%)

  Fly    10 PDGGYGWIVVAAVALINMT----NQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGL 70
            |:||:||:||.|....|.:    :.|:..::..|...|.:|.::..|.||.:   .:||:... .
Human    95 PEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWV---GALAMGMI-F 155

  Fly    71 FIGPAIKSFKPR---NVAAT-GCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAI 131
            |..|.:..|..|   .:.|| |..:..:||...:|.|........|....|.|.......:.:.:
Human   156 FCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVIL 220

  Fly   132 NSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGF--RYAVLS--MSSLSLFGLFGAAFLK 192
            ..||..:.|.|.||..||:.:..:..|.|:|.|.|....  .:.|||  |..|.|..|    ..:
Human   221 GHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVLMLLSL----TYR 281

  Fly   193 PLNPPAKHNNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDLE 257
            ||.|.::....|.                                .|.||..|...:|.:..::.
Human   282 PLLPSSQDTPSKR--------------------------------GVRTLHQRFLAQLRKYFNMR 314

  Fly   258 LLKDLVF--WSI-IVGMALVY--------------TATINFTMIFPGFLGQTAQLNSQMVAFCMS 305
            :.:...:  |:. |...||.|              .:.|..|.:....:|.|:.|...:......
Human   315 VFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHISD 379

  Fly   306 LVAGADIVFRLLLPIVTDHLRIPYRVVFLIGIVGLFVARCVLAENQTLPVIITMSVLTGMMKSAT 370
            .:.|...::..:|..:            |:|::.:.:..|     :....:|.:.:..|:.....
Human   380 SIPGLKKIYLQVLSFL------------LLGLMSMMIPLC-----RDFGGLIVVCLFLGLCDGFF 427

  Fly   371 VINNNLTISAHCRSEKLAG--------GLGLSMMSKGVIVITVGQLLGWVRDYADSYLICLYAQG 427
            :     ||.|....| |.|        |..|.||:  :.:|....:.|.:|:....|.:..|..|
Human   428 I-----TIMAPIAFE-LVGPMQASQAIGYLLGMMA--LPMIAGPPIAGLLRNCFGDYHVAFYFAG 484

  Fly   428 V--ILLVVVLVWTPEILYR--HRRQRCATNKSM 456
            |  |:..|:|.:.|.:..|  .:.||.::...|
Human   485 VPPIIGAVILFFVPLMHQRMFKKEQRDSSKDKM 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS_MCT_SLC16	15..440	CDD:340910	95/463 (21%)
SLC16A2	NP_006508.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92
		MFS_MCT8_10	100..498	CDD:340978	95/462 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	508..539		3/10 (30%)