Protein Alignment CG8389 and SLC16A1

DIOPT Version :9

• Sequence 1: NP_611076.2
• Gene: CG8389 / 36764
• FlyBaseID: FBgn0034063
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001159968.1
• Gene: SLC16A1 / 6566
• HGNCID: 10922
• Length: 500
• Species: Homo sapiens
• Alignment Length: 498
• Identity: 119/498 - (23%)
• Similarity: 204/498 - (40%)
• Gaps: 71/498 - (14%)

  Fly    10 PDGGYGW-IVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLFIG 73
            ||||:|| :|:.|...|..:.....|:  .:|..|::.:...|.:.....:...||:.:.|   |
Human    14 PDGGWGWAVVIGAFISIGFSYAFPKSI--TVFFKEIEGIFHATTSEVSWISSIMLAVMYGG---G 73

  Fly    74 P----AIKSFKPRNVAATGCILVALGLALCAFAS--ESWHFILGYSFFVGFGLGL---ISPSTFM 129
            |    .:..:..|.|...|..|...||...:|.:  :..:..:|   .:| ||||   ::|:..|
Human    74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIG---VIG-GLGLAFNLNPALTM 134

  Fly   130 AINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPL 194
             |..||..:|..|.|:::||:.:....:..|.:......|:|.:.|.:..|.|......|.::|:
Human   135 -IGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPI 198

  Fly   195 NP-PAKHNNRKHIRLLTEADGEKT--SPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDL 256
            .| |.|....|     ::|..||.  |.::..:...|...|.|.|....   ..:.|.:.|.:||
Human   199 GPKPTKAGKDK-----SKASLEKAGKSGVKKDLHDANTDLIGRHPKQEK---RSVFQTINQFLDL 255

  Fly   257 ELLKDLVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIV 321
            .|.....|...:.|..:::.. :...::|....|::...:|:..||.:|::|..|:|.|..:.:|
Human   256 TLFTHRGFLLYLSGNVIMFFG-LFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLV 319

  Fly   322 TDHLRIPYRVVFLIGIVGLFVARCVLAE---NQTLPVIIT---MSVLTGMMKSATVINNNLTISA 380
            .:...|..|:.:       |.|..|:|.   :...|:..|   ..|..|....|....:::..
Human   320 ANTKPIRPRIQY-------FFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLF-- 375

  Fly   381 HCRSEKLAGGLGLSMMSKGVIVITVGQ---------LLGWVRDYADSYLICLYAQGVILLV--VV 434
                |.|...:|....|..|.::|:.:         |||.:.|....|....:|.||:|::  :.
Human   376 ----ETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIY 436

  Fly   435 LVWTPEILYR--HRRQRCATNK---SMETQSIDAA----EVAK 468
            |.....|.||  .:.|:....|   ..|..|||.|    ||.|
Human   437 LFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTK 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	94/432 (22%)
		MFS_1	19..400	CDD:284993	87/398 (22%)
SLC16A1	NP_001159968.1	2A0113	1..455	CDD:273325	110/472 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	454..500		9/26 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820