DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and Slc16a8

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_113932.2	Gene:	Slc16a8 / 65200	RGDID:	69282	Length:	490	Species:	Rattus norvegicus

Alignment Length:	487	Identity:	108/487 - (22%)
Similarity:	177/487 - (36%)	Gaps:	97/487 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PDGGYGWIVVAAVALIN---MTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLF 71
            ||||:||:|:.|..:|.   ......:|||.:....:......||   |.::::....|..:|..
  Rat    13 PDGGWGWVVLGACFVITGFAYGFPKAVSVFFRELKRDFGAGYSDT---AWVSSIMLAMLYGTGPL 74

  Fly    72 IGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGL-ISPSTFMAINSYF 135
            ....:..|..|.|...|.:|.:.|:.|.:|||......|......|.||.| ..||..| :..||
  Rat    75 SSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLGLALNFQPSLIM-LGLYF 138

  Fly   136 TTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLNPPAKH 200
            ..:|..|.|::.||:.:....:..|.:.|.:..|:|...|....|.|......|.::|  ||..
  Rat   139 ERRRPLANGLAAAGSPVFLSTLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRP--PPGP- 200

  Fly   201 NNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDLELLKDLVFW 265
                                        |.:.:.:||.     .|...|  |.:||.:..|..|
  Rat   201 ----------------------------QPRPDPAPPG-----GRARHR--QLLDLAVCTDRTF- 229

  Fly   266 SIIVGMALVYTATINFTM----IFPGFL----GQTAQLNSQMVAFCMSLVAGADIVFR------- 315
                   :||..| .|.|    ..|..|    .:.|.:.....||.:|:|...|||.|
  Rat   230 -------MVYMVT-KFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALA 286

  Fly   316 ---LLLPIVTDHLRIPYRVVFLIGIVGLFVARCVLAENQTLPVIITMSVLTGMMKSATVINNNLT 377
               .|.|      .:||  :|.:.::...:...:.|..::...::...:..|:............
  Rat   287 GLGRLRP------HVPY--LFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEV 343

  Fly   378 ISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVRDYADSYLICLYAQG--VILLVVVLVWTPE 440
            :.|...:.:....|||.::.:.|.|:......|.:.|...:|.|..|..|  |:|..|.:..|
  Rat   344 LMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLAGSEVVLAGVFMAVT-- 406

  Fly   441 ILYRHRRQRC---------ATNKSMETQSIDA 463
               .:..|||         |...:.:|:.::|
  Rat   407 ---TYCCQRCSKDIPPGPSAEGGTSDTEDVEA 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	89/427 (21%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	83/402 (21%)
Slc16a8	NP_113932.2	2A0113	14..440	CDD:273325	107/486 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910