DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and slc16a6b

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_001352167.1	Gene:	slc16a6b / 561766	ZFINID:	ZDB-GENE-110208-3	Length:	527	Species:	Danio rerio

Alignment Length:	521	Identity:	112/521 - (21%)
Similarity:	193/521 - (37%)	Gaps:	101/521 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VPDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDT----------------FTAALI 57
            |||||:||:|.||...:.:....|:..|| :|:.:|.....:|                |||.|.
Zfish    16 VPDGGWGWMVAAAFFFVEVFTYGIIKTFG-IFLQDLMTEFHETNSRVSWAVSICVFVMAFTAPLS 79

  Fly    58 TNLNSLALNFSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGL 122
            |.|::               .|..|.|...|..|::||....|.........:......|.|..|
Zfish    80 TLLSN---------------RFGHRPVVMVGGFLISLGTITTALTQSIDEMYITMGIVAGLGYCL 129

  Fly   123 ISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFG 187
            ....|...::.||:.:|.....::..|.....:.....:..|.:..|:||.::.:..|....:..
Zfish   130 TFLPTVTILSQYFSKRRSLVTSIASTGECFSMLAFAPAMNALKEQIGWRYCLMVIGVLQASIIVC 194

  Fly   188 AAFLKPL----NPPAKHNNRKHIRLLT---EADGEKT--------------SPLQVVIVPTNQSK 231
            .|.|||:    .|..:..:...:::|.   :|:.|.|              |..||.:....|.|
Zfish   195 GALLKPIVIKPKPATQEASTSPLKVLDSKYDAENEFTCTSFDSVDSGVQSISSSQVNLAKEQQKK 259

  Fly   232 IE--RSP------PNVDTLCSRMGQRLVQAMDLELLKDLVF-WSIIVGMALVYTATINF--TMIF 285
            .|  .||      ...|:..||     .:.:|..:|:|..| ...:.|:    .||:.|  ..|:
Zfish   260 EEEGESPETPLKQKQEDSSVSR-----TKLLDFSVLRDASFNCYALFGL----FATLGFFAPQIY 315

  Fly   286 PGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIVTDHLRIPYRVVFLIGIVGLFVARCVLAEN 350
            ...|..:..::.:...:.:|.:|.|:|..||.:..|.:  |.|.|.::::.|       |.:...
Zfish   316 IIQLSVSRGVSQKSATYMLSAMAVAEIGGRLSMGWVLN--RKPIRKIYILLI-------CTVLLC 371

  Fly   351 QTLPVIITMSVLTGMMKSATVINNNLTISAHCRSEKLAGG--LGLSMMSKGVIVITV-------- 405
            ..|.|...:|...|:|..:.:....|...|......||..  :|:..||..|.|...
Zfish   372 PVLVVFTFVSEFWGLMSCSCLYGFLLGTVASSHIPMLAEDDVIGIQRMSSAVGVYVCIQSFAGLA 436

  Fly   406 -----GQLLGWVRDYADSYLICLYAQGVILLVVVLVWTPE--ILY--RHRRQRCATNKSMETQSI 461
                 |.|:....:|..::..|....||..|.:.||...:  :.:  |.|:.:.:.::...:|..
Zfish   437 GPPLGGFLVDQTNNYGSAFYSCAAGMGVGALFLGLVRPAKTGLCFGKRKRKDQQSADRDASSQGS 501

  Fly   462 D 462
            |
Zfish   502 D 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	95/468 (20%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	89/430 (21%)
slc16a6b	NP_001352167.1	2A0111	17..512	CDD:331689	111/520 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920