DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8389 and slc16a1

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_001015931.1	Gene:	slc16a1 / 548685	XenbaseID:	XB-GENE-1014566	Length:	490	Species:	Xenopus tropicalis

Alignment Length:	503	Identity:	107/503 - (21%)
Similarity:	201/503 - (39%)	Gaps:	88/503 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PDGGYGWIVVAAVAL-----------INMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNS- 62
            |:||:||:||.|..:           |.:..:.|.::||.              |::.::.::|
Frog    14 PEGGWGWVVVVAAFVSIGFSYAFPKSITVFFKDIEAIFGA--------------TSSEVSWISSI 64

  Fly    63 -LALNFSGLFIGP----AIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGL 122
             ||:.::|   ||    .:..:..|.|...|..|...||...:|.:......|......||||..
Frog    65 MLAVMYAG---GPISSVLVNKYGSRPVMIAGGCLAGTGLIAASFCNTVAELYLCIGVVGGFGLAF 126

  Fly   123 -ISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLF 186
             ::|:..| |..||..||..|.|:::||:.:....:..|.:|.....|:|.:.|.:..|......
Frog   127 NLNPALTM-IGKYFFKKRPIANGLAMAGSPVFLSTLAPLNQYFYSIFGWRGSFLILGGLLFNCCV 190

  Fly   187 GAAFLKPLNPPAKHNNRKHIR-LLTEA-------DGEKTSPLQVVIVPTNQSKIERSPPNVDTLC 243
            ..:.::|:.|..:...:|..: :|.||       ||:           .::..||.......||.
Frog   191 AGSLMRPIGPKPEDTKKKVTKEVLEEAGKCVSKEDGD-----------AHKDLIEGKAKTKPTLF 244

  Fly   244 SRMGQRLVQAMDLELLKDLVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVA 308
                |.:.:.:||.|.....|...:.|..:::.. :...::|.....::..::.:..||.:|::|
Frog   245 ----QTINKFLDLSLFTHRGFLLYLSGHMIMFFG-LFAPLVFLSNYAKSKNISPESAAFLLSILA 304

  Fly   309 GADIVFRLLLPIVTDHLRIPYRVVFLIGIVGLFVARCVLAENQTLPV---IITMSVLTGMMKSAT 370
            ..|::.|..:.||.:...:..::.:...:..|:...|.|    .:|:   .:...:..|....|.
Frog   305 IVDMIARPSMGIVANTKWVRPKIQYFFAVAVLYNGICHL----LVPLSTSYVGFCIYAGFFGFAF 365

  Fly   371 VINNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQ---------LLGWVRDYADSYLICLYAQ 426
            ...:::..      |.|...:|....|..|.::|:.:         |||.:.|....|.....|.
Frog   366 GWLSSVLF------ETLMDLVGAQRFSSAVGLVTIVECCPVLLGPPLLGRLNDIYGDYKYTYQAC 424

  Fly   427 GVILLV--VVLVWTPEILYR--HRRQRCATNKSMETQSIDAAEVAKLN 470
            |::|:|  |.|.....|.||  .:.|:....|:.|..:  .|...|:|
Frog   425 GIVLIVASVYLFIGMTIHYRLLAKEQKAEQKKAQEANA--GASENKVN 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	86/443 (19%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	79/409 (19%)
slc16a1	NP_001015931.1	2A0113	6..471	CDD:273325	107/503 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920