DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and slc16a12

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_989310.1	Gene:	slc16a12 / 394932	XenbaseID:	XB-GENE-1012784	Length:	473	Species:	Xenopus tropicalis

Alignment Length:	472	Identity:	102/472 - (21%)
Similarity:	187/472 - (39%)	Gaps:	76/472 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLFIGP 74
            ||||:||::|.....:.:..:::.......||.......:|....|.|.::    ::.|.:...|
Frog    13 PDGGWGWMIVIGCFFVTVCTRAVTRCISIFFVEFQSYFAQDYARTAWIHSI----VDCSTMLCAP 73

  Fly    75 AIKSFKPRNVAA-----TGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINSY 134
             |.|:...:.:.     .|.:|.:.||.|.:||:...:..|......|.|..|........:..|
Frog    74 -IGSYVSNHFSCQVGIILGGVLASTGLVLSSFATSLEYLYLTLGVLTGLGFALCYSPAIAMVGKY 137

  Fly   135 FTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSM----SSLSLFGLFGAAFLKPLN 195
            |..::..|.|::::|:|:|..::..:|:.|::...:|.|:|.:    |:|.:.|    |.::|:.
Frog   138 FEKRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVSNLCVCG----ALMRPIT 198

  Fly   196 PPAKHNNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPP---NVDTLCSRMGQ-----RLVQ 252
              .|.::..:                    |..|.::|..|.   .:|:.||.:.|     ||..
Frog   199 --LKEDSLHY--------------------PLKQEQMENEPTQSGRLDSSCSPLCQDCSHKRLCY 241

  Fly   253 AMDLE---LLKDLVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVF 314
            ....|   |||.......:..:.|.|..:..|..:.|..|  ...:::|..||.||::...|||.
Frog   242 CTKKEYSFLLKPKFMVLAVSFLFLAYGCSPPFVYLVPYAL--NVGVSNQEAAFLMSILGIIDIVG 304

  Fly   315 RLLLPIVTD------HLRIPYRVVFLIGIVGLFVARCVLAENQTLPV------IITMSVLTGMMK 367
            .:....|||      |....|.:.  :|:.||    |.|    .||:      ::..||:.|...
Frog   305 NITFGWVTDTRFLKKHRYCCYLIA--VGLDGL----CCL----FLPILTRFQLLVPFSVMFGYFD 359

  Fly   368 SATVINNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVRDYADSYLICLYAQGV-ILL 431
            .|.|....:.......:..|:..||:......|..:....:.||:.|....|.......|. ::.
Frog   360 GAYVALIPVVTGDVVGTSSLSSALGVVFFLHAVPYLVSPPIAGWLVDTTGDYTAAFLLSGFSMIF 424

  Fly   432 VVVLVWTPEILYRHRRQ 448
            ..||:...:|:.|.:::
Frog   425 CAVLLALAKIINRIKKR 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	91/437 (21%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	86/412 (21%)
slc16a12	NP_989310.1	2A0111	12..444	CDD:331689	102/472 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020