DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8389 and CG10019

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_001368939.1	Gene:	CG10019 / 33600	FlyBaseID:	FBgn0031568	Length:	1159	Species:	Drosophila melanogaster

Alignment Length:	507	Identity:	105/507 - (20%)
Similarity:	200/507 - (39%)	Gaps:	119/507 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VQSSRV----VPDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDT---FTAALITNL 60
            |.::|:    .||||:|||:.....|:::....:...:|.|:...:|.:...:   ...||..::
  Fly   428 VDTTRIRQYFYPDGGWGWIICGVSFLVHILTTGLQLSYGLLWFYAVQYLHNTSGIELLGALSWSV 492

  Fly    61 NSLALNFSGLFIGPAIKSFKPRNV---AATGCILVALGLALCAFASESWHFILGYSFFVGFGLGL 122
            :.:|.:|       .:...:.|::   :..|.:::.||:...:||:|....:..|....|.|:.:
  Fly   493 SMVATSF-------VVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAM 550

  Fly   123 ISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYA---VLSMSSLSLF- 183
            :..::.:.:.:||..:|.....|:::|.|:|..|...:::..:...|:|..   |.::::||.|
  Fly   551 VREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFM 615

  Fly   184 GLF--GAAFLKPLNPPAKH--NNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCS 244
            ||.  .|:...|.....:|  |.||.:|       ||.        |.....:|.:|...
  Fly   616 GLMYRPASLYHPQRRAIQHLKNQRKKMR-------EKK--------PILSQDVESTPKYF----- 660

  Fly   245 RMGQRLVQAMDLELLKDLVFWSIIVGMALVYTATINFTMIFPGFL--------GQTAQ---LNSQ 298
                    .:|:..||     |:.|.:.|:.::..:|.:..|.||        |...|   |...
  Fly   661 --------FLDISSLK-----SVTVKILLMTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQT 712

  Fly   299 MVAFCMSL---VAGA---------------DIVFRLLLPIVTDHLRIPYRVVFLIGIVGLFVARC 345
            .:...|:|   :|||               .||.:|.|.||.  |.|.: :.|::|..||    |
  Fly   713 FLGISMALGVVIAGALLRRCFVIRHFVINTKIVTQLFLSIVA--LAILF-LSFVMGYTGL----C 770

  Fly   346 VLAENQTLPVIITMSVLTGMMKSATVINNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLG 410
            :|            |.|.|:.......:..:......:.:..:...|.....:.|.|:....|..
  Fly   771 IL------------SWLYGIGLGGFQYSLKILALERIKLKHFSKAWGFIRGVESVPVLISVPLTS 823

  Fly   411 WVRDYA-----DSYLICLYAQGVILLVVVLVWTP--------EILYRHRRQR 449
            ::.||:     ..|.||..|..:..:::..:..|        :.|:.|.:||
  Fly   824 FLNDYSLKYGRAGYYICSAAAAISGIIIFFISEPQQQHQQQQQQLHHHYQQR 875

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	90/453 (20%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	82/423 (19%)
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	91/454 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020