DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8389 and CG14196

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_573367.1	Gene:	CG14196 / 32915	FlyBaseID:	FBgn0031002	Length:	600	Species:	Drosophila melanogaster

Alignment Length:	575	Identity:	144/575 - (25%)
Similarity:	237/575 - (41%)	Gaps:	127/575 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DVQSSRVVPDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALN 66
            |:....|.||.|:.|||..|..:.|::....|..||.||...|..:...:.....|.|.|.....
  Fly    29 DLGDDFVAPDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQITAIINANPAVSA 93

  Fly    67 FSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAI 131
            .:||..||..:.|..|.||..|.:|::..|.|.||......:::.|:...|||:|:...::.:||
  Fly    94 CTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISVSASSLAI 158

  Fly   132 NSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLF------------- 183
            |:||..||.||.|.|....|||.:.:||||.:||..:|.:...|..:::||.
  Fly   159 NTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRY 223

  Fly   184 --------------------------------GLFGAAFL--------------KPLNPPAKHNN 202
                                            |:|.:.:|              :|..|.....|
  Fly   224 HVKPPVEQLADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPGTPMLSRAN 288

  Fly   203 -------------RKHIRLLTEA-DGEKTSPLQVVI-----------VPTNQSKIERSPPNVDT- 241
                         |...|.::.: |.|:|..|...|           :..|..:.||...|::.
  Fly   289 DGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRERVESNLEAK 353

  Fly   242 LCSRMG-----------------------------------QRLVQAMDLELLKDLVFWSIIVGM 271
            ||.:..                                   .::|...||:||:|..|.:::.|:
  Fly   354 LCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRDFTFVNLVAGL 418

  Fly   272 ALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIVTDHLRIPY--RVVFL 334
            .::....:||:::.| |:......::..:...|||:||.||..|.::|.:|:  :||:  ||.||
  Fly   419 TIINFGELNFSILTP-FILVDFGFDTPQITLAMSLLAGLDITMRFMVPFLTE--KIPWDNRVFFL 480

  Fly   335 IGIVGLFVARCVLAENQTLPVIITMSVLTGMMKSATVINNNLTISAHCRSEKLAGGLGLSMMSKG 399
            ||:||:.:.|.|:|..::..:|:...|..|:.|....|...|.|..:....:|.|..||.::..|
  Fly   481 IGVVGIALGRTVVACTRSYSLILCSFVWIGLCKGVRTIFWPLIIPGYVPLNRLPGASGLQLLISG 545

  Fly   400 VIVITVGQLLGWVRDYADSYLICLYAQGVILLVVVLVWTPE-ILYRHRRQRCATN 453
            :..:..|..:|.|||..| |.:.|:...::..|....|:.| ::.||||::...|
  Fly   546 LFTLIGGPFVGLVRDRYD-YSVTLHCLNMMSFVAATSWSLEALIRRHRRKQRLVN 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	128/527 (24%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	119/502 (24%)
CG14196	NP_573367.1	MFS	71..>221	CDD:119392	47/149 (32%)
CG14196	NP_573367.1	MFS	<410..579	CDD:119392	50/172 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I2686
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0010010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.920