DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and Slc16a12

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_001178566.1	Gene:	Slc16a12 / 309525	RGDID:	1311468	Length:	486	Species:	Rattus norvegicus

Alignment Length:	470	Identity:	105/470 - (22%)
Similarity:	194/470 - (41%)	Gaps:	76/470 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQK--MQEDTFTA----------ALITNLNS 62
            ||||:||::||...|:.:..:::.......|| |.|.  .|:.:.||          .|...|.|
  Rat    13 PDGGWGWMIVAGCFLVTICTRAVTRCISIFFV-EFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGS 76

  Fly    63 LALN----FSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLI 123
            :..|    .:|:.:|.               :|.:.||.|.:||:...|..|......|.|..|.
  Rat    77 VVSNQLSCQAGIMLGG---------------LLASTGLILGSFATSLKHLYLSLGVLTGLGFALC 126

  Fly   124 SPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGA 188
            .......:..||:.::..|.|::::|:|:|..::..:|:.|::...:|.|:|.:....|......
  Rat   127 YSPAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCG 191

  Fly   189 AFLKPL------NPPAKHNNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCSRMG 247
            |.::|:      :.|.|.::|...|    .|.::.||...:.....::::         .||
  Rat   192 ALMRPITLKEDPSGPEKSHDRDAQR----EDCKQASPYSPLTKEWTETRL---------CCS--- 240

  Fly   248 QRLVQAMDLELLKDLVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADI 312
              |.|.....|:.|.|..::.| :.:.|..:..|..:.|..|  :..::....||.||::...||
  Rat   241 --LQQGYGFLLMSDFVVLAVSV-LFMAYGCSPLFVYLVPYAL--SVGVSHHQAAFLMSILGVIDI 300

  Fly   313 VFRLLLPIVTDHLRIP-YRVV---FLIGIVGLFVARCVLA--ENQTLPVIITMSVLTGMMKSATV 371
            |..:....:||...:. ||.|   |.:.:.||    |.|.  ..|:.|:::..|...|....|.|
  Rat   301 VGNITFGWLTDRRCLKNYRYVCYLFAVALDGL----CYLCLPMLQSFPLLVPFSCTFGYFDGAYV 361

  Fly   372 INNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVRD----YADSYLICLYAQGVILLV 432
            ....:..:....:..|:..||:......|..:....:.||:.|    |..::|:|.:|   ::..
  Rat   362 TLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFA---MIFS 423

  Fly   433 VVLVWTPEILYRHRR 447
            .:|:...:|..|.:|
  Rat   424 SILLGFAKIAKRMKR 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	94/437 (22%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	87/408 (21%)
Slc16a12	NP_001178566.1	2A0111	12..451	CDD:331689	105/470 (22%)
Slc16a12	NP_001178566.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..221		5/23 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920