DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and Slc16a7

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_058998.2	Gene:	Slc16a7 / 29735	RGDID:	3691	Length:	489	Species:	Rattus norvegicus

Alignment Length:	503	Identity:	105/503 - (20%)
Similarity:	200/503 - (39%)	Gaps:	104/503 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PDGGYGWIVVAAVALINMTNQSILSV-FG-------QLFVGELQKMQEDTF--TAALITNLNS-- 62
            ||||:||:||.|         |.:|: |.       .:|..::    :|.|  |::.|..::|
  Rat    20 PDGGWGWVVVCA---------SFISIGFSYAFPKAVTVFFNDI----KDIFKTTSSQIAWISSIM 71

  Fly    63 LALNFSGLFIGP----AIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLI 123
            ||:.::|   ||    .:.::..|.|...|.:|...|:.|.:|:|......|...|..|.||...
  Rat    72 LAVMYAG---GPISSVLVNNYGSRPVVIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLGLAFN 133

  Fly   124 SPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGA 188
            .......|..||..||..|.|.::||:.:....:....::|.:::|::.:.|.:.::.|......
  Rat   134 LQPALTIIGKYFYRKRPLANGFAMAGSPVFLSTLAPFNQFLFNSYGWKGSFLILGAIFLHSCVAG 198

  Fly   189 AFLKPLNP---PAKHNNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRL 250
            ..::|:.|   .||..::                     |.:.|....:....|.|     .:::
  Rat   199 CLMRPVGPSPRAAKSKSK---------------------VGSRQDSSTKRLSKVST-----AEKI 237

  Fly   251 VQAMDLELLKDLVFWSIIVGMALVYTATINFTMIFPGFLGQTAQ---LNSQMVAFCMSLVAGADI 312
            .:.:|..|.....|...:.|..:::...  |..|.  ||...|:   ::....||.:|::|..|:
  Rat   238 NRFLDFGLFTHRGFLIYLSGNVVLFLGM--FAPII--FLAPYAKDKGVDDYNSAFLLSVMAFTDM 298

  Fly   313 VFRLLLPIVTDHLRIPYRVVFLIGIVGLFVA----RCVLAENQTLPVIITMSVLTGMMKSATVIN 373
            ..|..:.::.:...|..|:.:|..:..:|..    .|.||.:.|..|:..:....|....::::
  Rat   299 FARPSVGLIANTSLIRPRIQYLFSVAIMFTGICHLLCPLAHSYTALVVYVIFFGIGFGSISSLL- 362

  Fly   374 NNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQ---------LLGWVRDYADSYLICLYAQGVI 429
                      .|.|...:|.|..|..|.::|:.:         |.|.:.|....|.....|.|::
  Rat   363 ----------FECLMDQVGASRFSSAVGLVTIVECCPVLFGPPLAGKLLDITGQYKYLYIASGIV 417

  Fly   430 LLV--VVLVWTPEILYR----------HRRQRCATNKSMETQSIDAAE 465
            :|.  :.|:....|.||          .||::.|:..|.|.:::..::
  Rat   418 VLSSGIYLLICNAINYRLLEKERKREKARRKKSASQASKEMEALSRSK 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	86/440 (20%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	80/406 (20%)
Slc16a7	NP_058998.2	2A0113	21..436	CDD:273325	99/471 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	206..227		5/41 (12%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	441..489		5/25 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920