DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and Slc16a4

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_001013935.1	Gene:	Slc16a4 / 295356	RGDID:	1359655	Length:	500	Species:	Rattus norvegicus

Alignment Length:	490	Identity:	94/490 - (19%)
Similarity:	195/490 - (39%)	Gaps:	84/490 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLFIGP- 74
            |||:||:||....|:|:....:...|...||...::.:..:.....|.::.| :|.||.   ||
  Rat    16 DGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMS-SLRFSA---GPL 76

  Fly    75 -AI--KSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINSYFT 136
             ||  ..|..:..:..|..||:.|..:.::|:......:......|.|...:.....:.|..||.
  Rat    77 AAIICDIFGEKTTSILGTFLVSGGYLISSWATGIPFLCVTMGLLPGLGSAFLYQVAAVVITKYFK 141

  Fly   137 TKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLN------ 195
            .:.|.:..::.:|.||..:|.| ..:.|:|.:.:..|::...:::|..:..:..|:|::
  Rat   142 KRLGLSTAIARSGMGLTFLLAP-FTKLLIDLYDWTGALILFGAIALNLVPSSMLLRPVHIQSDSN 205

  Fly   196 --------------PPAKH------NNRKHIRLLTEA----DGEKTSPLQVVIVPTNQSKIE--- 233
                          |...|      .|:....|:.::    .|:.|:.|.|:     :::||
  Rat   206 SDIKNKGSILSATGPELSHKTETPNRNKAQESLIKDSAVKKSGQPTTTLTVL-----ENQIEEIS 265

  Fly   234 ----RSPPNVDTLCSRMGQRLV------QAMDLELLKDLVF----WSIIVGMALVYTATINFTMI 284
                |:.|.:.:......::.|      :.:|:.|.::..|    ||.::.....:..|.:...
  Rat   266 TRPHRNRPLLMSNDKTYKKKFVSWNCKEKLLDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVA- 329

  Fly   285 FPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIVTDH---LRIPYRVVFLI--GIVGLFVAR 344
                ..:|..::....::.:|:....:.|.:|:...:.|.   .:..|...:||  |:..|....
  Rat   330 ----RAKTLGIDIMDASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKAYLILCGVTNLLAPL 390

  Fly   345 CVLAENQTLPVIITMSVLTGMMKS---ATVINNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVG 406
            ..     |.|:::..::...:...   |.::...:.:|.:.|..:.   ||.:....|:.|::..
  Rat   391 AT-----TFPLLMAYTIFFAIFAGGYLALILPVLVDLSKNSRVHRF---LGYASFFAGMAVLSGP 447

  Fly   407 QLLGWVRDYADSYLICLYAQGV--ILLVVVLVWTP 439
            .:.||:.||..:|:...|..|.  ||..|.|.:.|
  Rat   448 PIAGWIYDYTQTYVGSFYFSGTCYILSSVSLFFVP 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	81/464 (17%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	74/439 (17%)
Slc16a4	NP_001013935.1	MFS_MCT5	20..486	CDD:340979	91/486 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820