DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and Slc16a5

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_001074403.1	Gene:	Slc16a5 / 217316	MGIID:	2443515	Length:	468	Species:	Mus musculus

Alignment Length:	427	Identity:	91/427 - (21%)
Similarity:	148/427 - (34%)	Gaps:	114/427 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DGGYGWIVVAAVALINMTNQSILSVFGQ---LFVGELQK-MQEDTFTAALITNLNSLALNFSGLF 71
            ||.:.|:|:    |.::..|::...|..   :|..:||: .|......:...::....::..|..
Mouse     9 DGRWAWVVL----LSSLVTQALTLGFPTCIGVFFTDLQRDFQASNSETSWFPSILGAMVHGGGPL 69

  Fly    72 IGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINSYFT 136
            ....:|.|..|.....|.:|.:||:.:..|:....|..|......|.|:.....|:...:..||.
Mouse    70 CSILVKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLGMCFSFQSSITVVGLYFV 134

  Fly   137 TKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLNPPAKHN 201
            .:|..|..::..|..:|..|.|.|.||||:..|:|.|.|....:.|......|.|:|:
Mouse   135 RRRPLANALASMGLSMGVTLWPLLARYLLETLGWRGAFLIFGGILLHCCVCGALLRPV------- 192

  Fly   202 NRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDT-----LCSRMGQRLVQAMDLELLKD 261
                  ...|....|..||              .||.:.|     .|
Mouse   193 ------ATNEVPEPKEDPL--------------LPPKIPTRSCLATC------------------ 219

  Fly   262 LVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSL--VAGADIVFRL----LLPI 320
                          .:||.:.:.|        .:....:.||:.:  |...::.|.|    |:|.
Mouse   220 --------------VSTIRYHLAF--------DILRHNMGFCIYVTGVTWMNLGFALPHIFLVPY 262

  Fly   321 VTDHLRIPYRVVFLIGIVG---LF---VARCVLAENQTL--------PVIITMSVLTGMMKSATV 371
            ...|....|....|:.|||   :|   :|..:||..::|        .|.|.::.||.::
Mouse   263 AMHHGVDDYWAAMLMSIVGFCNIFLRPMAGLLLAGRKSLAAYRKYLFAVAILINGLTNLI----- 322

  Fly   372 INNNLTISAHCRSEKLAG---GLGLSMMSKGVIVITV 405
                .|:||..|  .|.|   ...|||...|::|..|
Mouse   323 ----CTVSADFR--VLLGYCLVYSLSMCGVGILVFQV 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	87/419 (21%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	84/412 (20%)
Slc16a5	NP_001074403.1	2A0113	8..461	CDD:273325	91/427 (21%)
		MFS	32..413	CDD:119392	84/400 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	429..468
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010