DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and Slc16a11

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_694721.2	Gene:	Slc16a11 / 216867	MGIID:	2663709	Length:	447	Species:	Mus musculus

Alignment Length:	450	Identity:	108/450 - (24%)
Similarity:	183/450 - (40%)	Gaps:	107/450 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PDGGYGWIVVAAVALINMTNQSILSVFGQLFVGEL-----QKMQEDTFTAALITNLNSLALNFSG 69
            ||||:||:|.||...:|..:..:|...| |.:.:|     :..|:..:.:||     :||:..:.
Mouse     9 PDGGWGWVVAAAAFAVNGLSYGLLRSLG-LALPDLAEHFERSAQDTAWVSAL-----ALAVQQAA 67

  Fly    70 LFIGPAIKS-FKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINS 133
            ..:|.|:.: :..|.|...|.:|.:|||...|||....|..||.....|.|..|:.......::.
Mouse    68 SPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSR 132

  Fly   134 YFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLNPPA 198
            ||:.:|..|||::|.|.|...:|:...:::|||..|:|.|:|.:.:::|......|.|:||
Mouse   133 YFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPL---- 193

  Fly   199 KHNNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDLELLKDLV 263
                        ...|:..:|             .|:|              :.|:.|.|.|...
Mouse   194 ------------ALSGDPLAP-------------PRTP--------------LAALGLGLFKRRA 219

  Fly   264 FWSIIVGMALV---YTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIVTDHL 325
            |....:|.||:   |  .:.:..:.|..|.|  .:.....|..:::.|..|...||....:.|..
Mouse   220 FSVFALGTALIGGGY--FVPYVHLGPHALDQ--GMGGYGAALVVAVAAVGDACARLASGWLADQG 280

  Fly   326 RIPY-RVVFLIG-IVGLFVARCVLA------ENQTLPVI---------------ITMSVLTGMMK 367
            .:|. |::.:.| :.||.|....|.      |....|::               :...||.|::.
Mouse   281 WVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPGLVG 345

  Fly   368 SATVINNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVG-QLLGWVR----DYADSYLIC 422
            ...|:.              |.||.:.:||.|.:   :| .|.|::|    |::.|:|:|
Mouse   346 IGGVVQ--------------ATGLVMMLMSLGGL---LGPPLSGFLRDKTGDFSASFLVC 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	100/440 (23%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	92/412 (22%)
Slc16a11	NP_694721.2	MFS	14..403	CDD:391944	103/444 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010