DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and gem-1

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_001379120.1	Gene:	gem-1 / 181458	WormBaseID:	WBGene00008214	Length:	771	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	65/283 - (22%)
Similarity:	114/283 - (40%)	Gaps:	51/283 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VVPDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQE--------DTFTAALITNLNSLA 64
            |..||||||:||.|..|::.........||.:||    |:||        ...||::..:|..:.
Worm    65 VYKDGGYGWLVVLASFLMHAVCDGASFCFGIVFV----KIQEHFQCGRFVSMITASMFLSLPLIM 125

  Fly    65 LNFSGL---FIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPS 126
            ...:|:   .:|..:......::....||       :..|.|..:.|::.:....|.|:..|..:
Worm   126 SPVAGIVSDILGCRMSIIIGASICTVSCI-------IAMFCSHIFFFMISFGLGCGVGMSFIYNA 183

  Fly   127 TFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAA-- 189
            ..:.:..||..:||.|...:::|.|:|.|:.|     :|.|....|....:|.:.:..:|.|.
Worm   184 AIVIVTYYFEKRRGLATSFAVSGTGVGTVIYP-----ILLNLSMIYLASFVSDIRIILIFFAVMY 243

  Fly   190 --------FLKPLNPPAKHNN---RKHIRLLTEADGEK---TSPLQVVIVPTNQSKIERSPPNVD 240
                    |:|.:...:...:   ||..:.:.:.|.||   |:|....:      :...|.||::
Worm   244 FVIAVIGFFIKDVEWESDKTDFKLRKFQKYIAKMDDEKENNTNPTDAFM------RHAISLPNLN 302

  Fly   241 TLCSRMG--QRLVQAMDLELLKD 261
            .|.:..|  |.:..|...|...|
Worm   303 ILNNHSGSIQSICDAAKAERKSD 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	57/272 (21%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	57/272 (21%)
gem-1	NP_001379120.1	MFS	72..>254	CDD:421695	43/197 (22%)
gem-1	NP_001379120.1	MFS	<543..727	CDD:421695
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820