Protein Alignment CG8389 and mct-4

DIOPT Version :10

• Sequence 1: NP_611076.2
• Gene: CG8389 / 36764
• FlyBaseID: FBgn0034063
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001041267.1
• Gene: mct-4 / 180766
• WormBaseID: WBGene00003986
• Length: 777
• Species: Caenorhabditis elegans
• Alignment Length: 632
• Identity: 109/632 - (17%)
• Similarity: 209/632 - (33%)
• Gaps: 222/632 - (35%)

  Fly    10 PDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLFIGP 74
            |||||||::|.|..:.|:....|.:.|.:......::.||   :..|...:.||.:. :.|.:||
 Worm    70 PDGGYGWVIVFAAFMSNLVVDGISTAFSEFKQSYKERYQE---SDGLTVFIGSLIIG-TYLLVGP 130

  Fly    75 AIKS----FKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINSYF 135
            .:.:    ::.|.|...|.::..:...:...:...:.|:|.|....|.|.|:|.....:.:..||
 Worm   131 LVSALCNKYEQRYVVMAGGLISGIAFMIAPASPNIYVFMLIYGVMGGLGFGMIYLPAIVVVGFYF 195

  Fly   136 TTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPL------ 194
            .:||..|.|:|:||:|:|..|:|.:.:..:.|.|::..:..::.:....:|.....:||
 Worm   196 DSKRAMATGISVAGSGVGTFLVPLICQVCIANLGWQKTIWVLAVMIFSCVFYGYLYRPLPMVDLN 260

  Fly   195 -------NP----------------PAKHNNR--------------------KHIR-LLTEAD-G 214
                   .|                .:.|.||                    :.:| :|||.| |
 Worm   261 EIRDQEMEPLRQALSKVEDDEDEAVESPHPNRSTSAASGAIEDEAVSQNPEVQRLRSILTEGDEG 325

  Fly   215 EKTS------------------------------------------------------------- 218
            .:|.
 Worm   326 SETPKSDAHKVRSHTATRSRKHTMTSNSGSQHDLKLSRGNLSSDNRLSRVSARDFNQSLSKLSKS 390

  Fly   219 -------------------------------------------------------PLQVVIVPTN 228
                                                                   |..||....:
 Worm   391 GGASNLSIAMSGVDPKEFQRPMNRQDIFYGGSIQNLKEFKEEGTMAGYRASTLSIPRSVVGQAVS 455

  Fly   229 QSKIERS-----------------PPNVDTLCSR-----MGQRLVQAMDLELLKD----LVFWSI 267
            |..:.|:                 .|.||..|.:     |...|.:.:||.|||:    ::..|.
 Worm   456 QLNLSRTGSRLGGPGIAEDEEEMIEPFVDDGCCKVLPLPMRNALSEMIDLNLLKNKTMMILCISN 520

  Fly   268 IVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIVTDHLRIPYRVV 332
            ::||...|     ..::|...|.::.:|:..:..|.:.:....:.:.|:....:||...:....:
 Worm   521 LLGMMGFY-----IPIMFLKDLSESMKLDMSLAMFLVPIFGVFNTIGRVFFGWLTDQKILSALTI 580

  Fly   333 FLIGIV--GLFVARCVLAENQTLPVIITM------SVLTGMMKSATVINNNLTISAHCRSEKLAG 389
            ..:.::  ||....|        |::.::      :::.|.:.||.:...::.::.....|.|..
 Worm   581 NNLSLIVSGLLTLAC--------PLLTSIAGQYFYAIVFGFIISAYICLTSIVLADLMGLENLTN 637

  Fly   390 GLGLSMMSKGVIVITVGQLLGWVRDYADSYLICLYAQGVILLVVVLV 436
            ..||.::::|:..:......|.|.|...||....|..|::|||..|:
 Worm   638 SFGLLVVARGIASLVGPPFAGIVYDITGSYDTAFYFGGLVLLVAGLI 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS_MCT_SLC16	15..440	CDD:340910	104/627 (17%)
mct-4	NP_001041267.1	MFS_MCT_SLC16	75..>252	CDD:340910	41/180 (23%)
		MFS	<507..689	CDD:475125	37/191 (19%)