Protein Alignment CG8389 and SLC16A11

DIOPT Version :10

• Sequence 1: NP_611076.2
• Gene: CG8389 / 36764
• FlyBaseID: FBgn0034063
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_699188.2
• Gene: SLC16A11 / 162515
• HGNCID: 23093
• Length: 447
• Species: Homo sapiens
• Alignment Length: 452
• Identity: 110/452 - (24%)
• Similarity: 178/452 - (39%)
• Gaps: 97/452 - (21%)

  Fly    10 PDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLFIGP 74
            ||||:||:|.||...||..:..:|...|..|....:.........|.|:.| :||:..:...:|.
Human     9 PDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISAL-ALAVQQAASPVGS 72

  Fly    75 AIKS-FKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINSYFTTK 138
            |:.: :..|.|...|.:|.:||....||||:..|..||.....|||..|:.......::.||:.:
Human    73 ALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRR 137

  Fly   139 RGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLNPPAKHNNR 203
            |..|||::|.|.|...:|:...::.|||..|:|.|:|.:.:::|......|.|.||..|
Human   138 RVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLP------ 196

  Fly   204 KHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDLELLKDLVFWSII 268
                      |:..:|             .|||              :.|:.|.|.....|....
Human   197 ----------GDPPAP-------------PRSP--------------LAALGLSLFTRRAFSIFA 224

  Fly   269 VGMALV---YTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIVTDHLRIPY- 329
            :|.|||   |  .:.:..:.|..|.:  .|.....|..:::.|..|...||:...:.|...:|.
Human   225 LGTALVGGGY--FVPYVHLAPHALDR--GLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLP 285

  Fly   330 RVVFLIGI---VGLFVARCV---------------------LAENQTLPVIITMSVLTGMMKSAT 370
            |::.:.|.   :||:|...|                     |:.....|::  ..||.|::....
Human   286 RLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLV--FGVLPGLVGVGG 348

  Fly   371 VINNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVG-QLLGWVRDYADSYLICLYAQGVILL 431
            |:.              |.||.:.:||.|.:   :| .|.|::||....:.......|.::|
Human   349 VVQ--------------ATGLVMMLMSLGGL---LGPPLSGFLRDETGDFTASFLLSGSLIL 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS_MCT_SLC16	15..440	CDD:340910	106/447 (24%)
SLC16A11	NP_699188.2	MFS	14..403	CDD:475125	106/447 (24%)