Protein Alignment CG8389 and SLC16A10

DIOPT Version :9

• Sequence 1: NP_611076.2
• Gene: CG8389 / 36764
• FlyBaseID: FBgn0034063
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_061063.2
• Gene: SLC16A10 / 117247
• HGNCID: 17027
• Length: 515
• Species: Homo sapiens
• Alignment Length: 498
• Identity: 116/498 - (23%)
• Similarity: 197/498 - (39%)
• Gaps: 112/498 - (22%)

  Fly    10 PDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKM--QED---TFTAALITNLNSLALNFSG 69
            |:||:||:|:.|....|.:...|.:..|.|||..|:..  ::|   .|..|.:.:| |:.:.|
Human    65 PEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSL-SMGMIF-- 126

  Fly    70 LFIGPAIKSFKP----RNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMA 130
             |..|.:..|..    |..|..|..:..:||...:|.|......|.|......|.......:.:.
Human   127 -FCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVI 190

  Fly   131 INSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAF-LKPL 194
            :..||..:.|...|:..||:.:..:|:|.|:|.|:|:.|..| .|.:..:.:|.||.|.| .:||
Human   191 LGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFY-TLRVLCIFMFVLFLAGFTYRPL 254

  Fly   195 NPPAKHNNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDLELL 259
            ....|..         |:.|..:|..         |:.:.|||.             :..:..:.
Human   255 ATSTKDK---------ESGGSGSSLF---------SRKKFSPPK-------------KIFNFAIF 288

  Fly   260 KDLVF--WSIIVGMALVYTATINFTMIFPGFLGQTAQL------------NSQMVAFCMSLVAGA 310
            |...:  |::.:.:||.            |:......|            |.::|..|:.:.:|
Human   289 KVTAYAVWAVGIPLALF------------GYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSG- 340

  Fly   311 DIVFRLLLPIVTDHL----RIPYRVV--FLIGIVGLFVARCVLAENQTLPVIITMSVLTGMMKSA 369
              |.|||...:.|::    ::..:|:  |.||::.:.:..|.:     ...:|.:.::.|:....
Human   341 --VGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSI-----FGALIAVCLIMGLFDGC 398

  Fly   370 TVINNNLTISAHCRSEKLAG--------GLGLSMMSKGVIVITVG-QLLGWVRDYADSYLICLYA 425
            .:     :|.|....| |.|        |..|..||   |.:||| .:.|.:||...||.:..|.
Human   399 FI-----SIMAPIAFE-LVGAQDVSQAIGFLLGFMS---IPMTVGPPIAGLLRDKLGSYDVAFYL 454

  Fly   426 QGVILLV--VVLVWTPEILYRHRRQRCAT------NKSMETQS 460
            .||..|:  .||.:.|.|..:.:|:...|      .|.:|.|:
Human   455 AGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQN 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	97/444 (22%)
		MFS_1	19..400	CDD:284993	88/418 (21%)
SLC16A10	NP_061063.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48
		2A0113	67..487	CDD:273325	112/484 (23%)
		MFS	71..470	CDD:119392	105/463 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820