DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8389 and slc16a14

DIOPT Version :9

Sequence 1:	NP_611076.2	Gene:	CG8389 / 36764	FlyBaseID:	FBgn0034063	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	XP_002944264.2	Gene:	slc16a14 / 100491705	XenbaseID:	XB-GENE-6049356	Length:	513	Species:	Xenopus tropicalis

Alignment Length:	525	Identity:	121/525 - (23%)
Similarity:	216/525 - (41%)	Gaps:	93/525 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QSSRVVP--DGGYGWIVVAA---VALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSL 63
            |..:|.|  |.|:.|:||.:   |.|:.|.:|..|.:.      .|:.::|...:..|...::||
Frog    21 QMKKVNPNIDRGWAWMVVLSSFLVHLLVMGSQMALGIL------NLEWLEEFKQSRGLTAWISSL 79

  Fly    64 ALNFSGLFIGPAIKSF----KPRNVAATGCILVALGLALCAFASESWHFILGYSFFV--GFGLGL 122
            ::..: |.:||.|..|    ..|..|..|..|.:||..|.|:| .:.||:. :||.|  |.|.|:
Frog    80 SMGIT-LIVGPIIGLFINTCGCRKTAMIGGFLTSLGWVLSAYA-PNVHFLF-FSFGVTAGIGSGM 141

  Fly   123 ISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFG 187
            :.....:.:..||..:|..|.|:|..|.|.|..||..|::||....|:|.|::...:::|.....
Frog   142 VYLPAVVTVGHYFQKRRALAQGLSTTGTGFGTFLITVLLKYLCRELGWRNAMIIQGAVTLNLCVC 206

  Fly   188 AAFLKPLNPPAKHNNRKHIRLLTEADGEKTSPLQVVIVPTNQS--KIERSPPNVDTLCSRMGQR- 249
            .|.::||:...:|........:...|.::.:.|.|..:..|..  :.|....:.||..|...:.
Frog   207 GALMRPLDHDEEHLKDHEEAAVDPKDAKEGALLNVNAIKANSELHEEEEGKASADTAVSWSKEET 271

  Fly   250 ----LVQAMD-LELLKDLVFWSIIV--GMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCM-SL 306
                .:..|: |.::|.|...::.|  |....|::....:.:|         .|...|||.. :|
Frog   272 RNDIFINDMNKLSIMKTLTHMTVSVRSGFFAWYSSYFGASSLF---------TNKVFVAFVFWAL 327

  Fly   307 VAGADIVFRLL-LPIVTDHLRIP-----YRVVFLIGIVGLF---------VARCV------LAEN 350
            :|....|...: ||.:.:...:.     :.:..:|.||.:|         ...||      :|.|
Frog   328 LAYCSFVIPFIHLPEIVEMYGLTEQNNIFPLTSIIAIVHIFGKVILGFLGDLPCVSAWNVFIASN 392

  Fly   351 QTLPVIITMSVLTGMMKSATVINNNLTISAHCRS------------EKLAGGLGLSMMSKGVIVI 403
            .||.|.|.:..|..:..|..::...:..|:...|            ::||...|:.:.:.|:..:
Frog   393 FTLGVSILILPLMHVYSSLALVCALIGFSSGYFSLMPVVTEDLVGIKQLANAYGIIICANGISAL 457

  Fly   404 TVGQLLGWVRD----YADSYLIC--LYAQGVILLVVVLVWTPEILYRHRRQRCATNKSMETQSID 462
            ......||:.|    |..|:.:|  ||..|:|.|::              :.|..:|...::.:.
Frog   458 LGPPFAGWIYDITQKYDYSFYVCGLLYMVGIICLLL--------------EPCLQSKDQPSKKLS 508

  Fly   463 AAEVA 467
            .::.|
Frog   509 GSQEA 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8389	NP_611076.2	MFS	19..425	CDD:119392	107/464 (23%)
CG8389	NP_611076.2	MFS_1	19..400	CDD:284993	99/433 (23%)
slc16a14	XP_002944264.2	MFS_MCT14	34..495	CDD:340987	113/492 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920