Protein Alignment CG8388 and Zfp827

DIOPT Version :10

• Sequence 1: NP_611075.1
• Gene: CG8388 / 36763
• FlyBaseID: FBgn0034062
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_006531305.1
• Gene: Zfp827 / 622675
• MGIID: 2444807
• Length: 1404
• Species: Mus musculus
• Alignment Length: 665
• Identity: 134/665 - (20%)
• Similarity: 206/665 - (30%)
• Gaps: 240/665 - (36%)

  Fly    63 NFYLNVEQAHKALEQTVLKETSPPEVVASALEEHIVKSEHDDSVAAAVKRRRGRPRKVAQQDARE 127
            :|.||.  |.:....|.||:  |.|.|:::.   .|....|.||..|             .|...
Mouse   580 SFTLNA--ADRPANHTKLKD--PSEYVSNSA---AVLFSQDISVKMA-------------SDFLM 624

  Fly   128 ELKSV--LEQINLNEIKIEFPEADLTIADVLEDQEEQDFLPDDCISKEG-AEDP-EVLEKKPPTL 188
            :|.:.  .|.:|||....|.|:.:.:::..| .:....|.|:..:|... :||| ...|.|...|
Mouse   625 KLSAANQKEPMNLNFKVKEEPKEEESLSMPL-PRSSYVFSPEPEVSTPSVSEDPLTPQEGKGSVL 688

  Fly   189 KRKVSGRSRGRRRVQLAE----------------------------------------RPNTSCL 213
            :|.:|.::.....::|:.                                        |..|..|
Mouse   689 RRDMSAKAASELLMKLSAESYKETQAVTVKEEPMEVDIQDSPASISPSRNIGYSTLMGREKTEPL 753

  Fly   214 PKIQKSQ---EFNDYIREHYKVQCHICNLPMEDFSEML----AHVRREHKQ-------------- 257
            .|:.:.:   |.|.:.::          :.::..||:|    ..|.:||..
Mouse   754 QKLPEGRVPPERNLFSQD----------ISVKMASELLFQLSEKVSKEHNHTKENAMRTTTSPFF 808

  Fly   258 -----RGYAMCCNRKFLKRGVLVDHLRRHQDPET--------------------FKCSICGRVMG 297
                 |......|.|.|..|..|.| .|...|||                    |.|.:||:|.|
Mouse   809 SEDTFRQSPFTSNSKDLLPGESVLH-GRVSAPETEKIVLEAGNGLPSWKFNDQLFPCDVCGKVFG 872

  Fly   298 HRRSLELHMRMHEI---KSRGRLYRCEQCSKAFYSAVVYERHKLTHIPREQWKVPCTHCE----- 354
            .:::|..|:.:|.:   ....|.|:|..|..|........:|...|    ..|:..|..|
Mouse   873 RQQTLSRHLSLHTVLVSPPEERKYKCHLCPYAAKCRANLNQHLTVH----SVKLVSTDTEDIVSA 933

  Fly   355 --------KTYPSQYTMQQHVKLVHLNLYAKICDVCGKSIRGREALARHMEEHTGGPQ--AAIKC 409
                    |.:|..|:                |.|||...........||..|....|  .:|.|
Mouse   934 VTSEGSDGKKHPYYYS----------------CHVCGFETELNVQFVSHMSLHVDKEQWMFSICC 982

  Fly   410 HLCDSMLTTKYGLARHIKMMHTAE---------------------------------------NL 435
            ..||.:...:..:..||...||.:                                       ||
Mouse   983 TACDFVTMEEAEIKTHIGTKHTGDDRKTPSESNSPSSSSLSTLSDSANGKDDSDSSQKNKGGNNL 1047

  Fly   436 ---------QP-----------MQCEFCLKICPSLQAHQHHIKYTHNTARSHQCPMCEKAFKRPN 480
                     ||           .:|.||..:|.:....:.|:: .|...|..:|.:|.|..|.|.
Mouse  1048 LVISVVPGSQPSLNNEEKPEKGFECVFCNFVCKTKNMFERHLQ-IHLITRMFECDVCHKFMKTPE 1111

  Fly   481 ELKEHMTTHT--------GEVLYTCPHCPQTFNSNANMHAHRKKVHRKEWEENRHKRLNRSRKSD 537
            :|.||...||        |:   .||.|..:.|..|.|..|.|..::.|:         :.|...
Mouse  1112 QLLEHKKCHTVPTGGLNSGQ---WCPFCIYSTNRPAAMECHLKTHYKMEY---------KCRICQ 1164

  Fly   538 TIIAVSVRKTTETRQ 552
            |:.|..:...|.||:
Mouse  1165 TVKANQLELETHTRE 1179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8388	NP_611075.1	zf-AD	3..78	CDD:462262	4/14 (29%)
		C2H2 Zn finger	264..281	CDD:275368	6/16 (38%)
		C2H2 Zn finger	289..309	CDD:275368	7/19 (37%)
		C2H2 Zn finger	320..340	CDD:275368	4/19 (21%)
		C2H2 Zn finger	350..369	CDD:275368	5/31 (16%)
		C2H2 Zn finger	440..461	CDD:275368	5/20 (25%)
		C2H2 Zn finger	469..489	CDD:275368	8/19 (42%)
		C2H2 Zn finger	497..515	CDD:275368	7/17 (41%)
Zfp827	XP_006531305.1	COG5048	399..>488	CDD:227381
		C2H2 Zn finger	421..441	CDD:275368
		C2H2 Zn finger	449..469	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368
		C2H2 Zn finger	864..884	CDD:275370	7/19 (37%)
		C2H2 Zn finger	898..918	CDD:275370	4/19 (21%)
		C2H2 Zn finger	1072..1092	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1100..1120	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1160..1180	CDD:275368	6/20 (30%)
		zf-H2C2_5	1186..1210	CDD:404746
		C2H2 Zn finger	1188..1208	CDD:275368
		zf-H2C2_2	1201..1225	CDD:463886
		C2H2 Zn finger	1216..1235	CDD:275368
		C2H2 Zn finger	1245..1265	CDD:275368