DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8388 and XAF1

DIOPT Version :9

Sequence 1:	NP_611075.1	Gene:	CG8388 / 36763	FlyBaseID:	FBgn0034062	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_011522247.1	Gene:	XAF1 / 54739	HGNCID:	30932	Length:	403	Species:	Homo sapiens

Alignment Length:	305	Identity:	61/305 - (20%)
Similarity:	95/305 - (31%)	Gaps:	128/305 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 CSICGRVMGHRRSLELHMRMHEIKSRGRLYRCEQCSKAFYSAVVYERHKLTHIPREQWKVPCTHC 353
            |::|.:.| .:.|||.|             :..:|                    ::..|.|..|
Human   161 CTMCQQSM-QKSSLEFH-------------KANEC--------------------QERPVECKFC 191

  Fly   354 EKTYPSQYTMQQHVKLVHLNLY-------AKICDVCGKSIRGREALARHME------------EH 399
                      :..::|..|.|:       .::|..||:.|..| .||:|.:            |.
Human   192 ----------KLDMQLSKLELHESYCGSRTELCQGCGQFIMHR-MLAQHRDVCRSEQAQLGKGER 245

  Fly   400 TGGPQAAIKCHLCDSMLTTKYGLARHIKMMHTAENLQPMQCEFCLKICPSLQAHQHHIKYTHNTA 464
            ...|:..|.||.|:.|:               .||                       ||.|:..
Human   246 ISAPEREIYCHYCNQMI---------------PEN-----------------------KYFHHMG 272

  Fly   465 RSHQCPMCEKAFKRPNELKEHMTTHTGEVLYTCPHCPQTFNSNANMHAHRKKVHRKEWEENR--- 526
            :.  ||        .:|.|:|......|:|.:........|..:.|   .|.|..|....||
Human   273 KC--CP--------DSEFKKHFPVGNPEILPSSLPSQAAENQTSTM---EKDVRPKTRSINRFPL 324

  Fly   527 HKRLNRSRKSDTIIAVSVRKTTETRQDGGLVPAEAIATTSSPRAE 571
            |.. :.|:|:..    |..||.:.     |:.:|....|||||.:
Human   325 HSE-SSSKKAPR----SKNKTLDP-----LLMSEPKPRTSSPRGD 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8388	NP_611075.1	zf-AD	<21..77	CDD:285071
		C2H2 Zn finger	264..281	CDD:275368
		C2H2 Zn finger	289..309	CDD:275368	7/19 (37%)
		C2H2 Zn finger	320..340	CDD:275368	1/19 (5%)
		C2H2 Zn finger	350..369	CDD:275368	2/18 (11%)
		C2H2 Zn finger	440..461	CDD:275368	2/20 (10%)
		C2H2 Zn finger	469..489	CDD:275368	5/19 (26%)
		C2H2 Zn finger	497..515	CDD:275368	2/17 (12%)
XAF1	XP_011522247.1	PLN03086	<157..222	CDD:178635	17/104 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000