DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8388 and CG7368

DIOPT Version :9

Sequence 1:	NP_611075.1	Gene:	CG8388 / 36763	FlyBaseID:	FBgn0034062	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001036599.1	Gene:	CG7368 / 39301	FlyBaseID:	FBgn0036179	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	222	Identity:	50/222 - (22%)
Similarity:	75/222 - (33%)	Gaps:	88/222 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 CTHCEKTYPSQYTMQQHVKLVHLNLYAK-ICDVCGKSIRGREALARHMEEHTGGPQAAIKCHLCD 413
            |..|...||....::.|  ||..||..: :||:|..|::.::.|.||
  Fly   330 CPECHVAYPEPELLEVH--LVGHNLEKRYVCDICQASLKRKDHLTRH------------------ 374

  Fly   414 SMLTTKYGLARHIKMMHTAENLQPMQCEFCLKICPSLQAHQHHIKYTHNTARSHQCPMCEKAFKR 478
                                                        |.:||..|.:.|.:|.|||||
  Fly   375 --------------------------------------------KQSHNPERPYICTVCLKAFKR 395

  Fly   479 PNELKEHMTTHTGEVLYTCPHCPQTFNSNANMHAHRKKVHRKEWEENRHKRLNRSRKSDTIIAVS 543
            ..:|..|...|:||..:.|..|.:.|        :||...||      |.|.:.:|:      |.
  Fly   396 KEQLSLHFVIHSGEKRHQCGECGKGF--------YRKDHLRK------HTRSHIARR------VK 440

  Fly   544 VRKTTETRQDGG---LVPAEAIATTSS 567
            ....:..|::.|   |.|....|||::
  Fly   441 AELNSHVRRENGTSMLQPVVTEATTAA 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8388	NP_611075.1	zf-AD	<21..77	CDD:285071
		C2H2 Zn finger	264..281	CDD:275368
		C2H2 Zn finger	289..309	CDD:275368
		C2H2 Zn finger	320..340	CDD:275368
		C2H2 Zn finger	350..369	CDD:275368	5/18 (28%)
		C2H2 Zn finger	440..461	CDD:275368	1/20 (5%)
		C2H2 Zn finger	469..489	CDD:275368	9/19 (47%)
		C2H2 Zn finger	497..515	CDD:275368	3/17 (18%)
CG7368	NP_001036599.1	C2H2 Zn finger	330..350	CDD:275368	7/21 (33%)
		COG5048	356..>412	CDD:227381	23/117 (20%)
		C2H2 Zn finger	358..378	CDD:275368	8/81 (10%)
		zf-H2C2_2	370..395	CDD:290200	12/86 (14%)
		C2H2 Zn finger	386..406	CDD:275368	9/19 (47%)
		zf-H2C2_2	399..423	CDD:290200	8/31 (26%)
		zf-C2H2	412..434	CDD:278523	9/35 (26%)
		C2H2 Zn finger	414..434	CDD:275368	9/33 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100