DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8388 and ZK686.5

DIOPT Version :9

Sequence 1:	NP_611075.1	Gene:	CG8388 / 36763	FlyBaseID:	FBgn0034062	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001023030.2	Gene:	ZK686.5 / 3565160	WormBaseID:	WBGene00022795	Length:	263	Species:	Caenorhabditis elegans

Alignment Length:	271	Identity:	61/271 - (22%)
Similarity:	99/271 - (36%)	Gaps:	67/271 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 REELKSVLEQINL-----------NEIKIE-FPE-ADLTIADVLEDQEEQDFLPDDCISKEGAED 177
            ||.||:..|...|           .|..:| .|| .|.||.     |.::.|..|:..:..|...
Worm    25 RETLKATKELCELMSHESVGCSCFQEFPVEKAPEMPDFTII-----QPDRKFDGDNAAAVAGIFV 84

  Fly   178 PEVLEKKPPTLKRKVSGRSRGRRRVQLAERPNTSCLPKIQKSQEFNDYIREHYKVQCHICNLPME 242
            ........|:....::.:.  |:.|.     |||    .:|...:.|..|::.:   .|.|:..:
Worm    85 RSSTSSSFPSASSYIAAKK--RKNVD-----NTS----TRKPYSYKDRKRKNTE---EIRNIKKK 135

  Fly   243 DFSEMLAHVR------REHKQRGYAMCCNRKFLKRGVLVDHLRRHQDPETFKCSICGRVMGHRRS 301
            .|.: |..||      .|.:.|..||  .||..:..|            |..|.:|.:.....:.
Worm   136 LFMD-LGIVRTNCGIDNEKQDREKAM--KRKVTETIV------------TTYCELCEQNFSSSKM 185

  Fly   302 LELHMRMHEIKSRGRLY-----RCEQCSKAFYSAVVYERHKLTHI-PREQWKVPCTHCEKTYPSQ 360
            |.||        ||:::     .|..|.|.|...:.:.||..||. |..:..|.|..|::.:..:
Worm   186 LLLH--------RGKVHNTPYIECHLCMKLFSQTIQFNRHMKTHYGPNAKIYVQCELCDRQFKDK 242

  Fly   361 YTMQQHVKLVH 371
            .:::.|..:.|
Worm   243 QSLRTHWDVSH 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8388	NP_611075.1	zf-AD	<21..77	CDD:285071
		C2H2 Zn finger	264..281	CDD:275368	3/16 (19%)
		C2H2 Zn finger	289..309	CDD:275368	5/19 (26%)
		C2H2 Zn finger	320..340	CDD:275368	6/19 (32%)
		C2H2 Zn finger	350..369	CDD:275368	3/18 (17%)
		C2H2 Zn finger	440..461	CDD:275368
		C2H2 Zn finger	469..489	CDD:275368
		C2H2 Zn finger	497..515	CDD:275368
ZK686.5	NP_001023030.2	C2H2 Zn finger	173..194	CDD:275368	7/28 (25%)
		C2H2 Zn finger	201..221	CDD:275368	6/19 (32%)
		zf-C2H2_8	<204..251	CDD:292531	12/46 (26%)
		C2H2 Zn finger	232..248	CDD:275368	2/15 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000909
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000