back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8388 and Zfp407

DIOPT Version :9

Sequence 1:	NP_611075.1	Gene:	CG8388 / 36763	FlyBaseID:	FBgn0034062	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_008770443.2	Gene:	Zfp407 / 307213	RGDID:	1310645	Length:	2255	Species:	Rattus norvegicus

Alignment Length:	548	Identity:	131/548 - (23%)
Similarity:	202/548 - (36%)	Gaps:	118/548 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 EQTVL-KETSPPEVVASALEEHIVKSEHDDSVAAAVKRRR-----GRPRKVAQQDAREELKSVLE 134
            |:.|| |...|.::......|.|      ..|...:.|.:     |...||..:...|:||.|..
  Rat  1231 EEKVLDKSPCPGDLDGGHSAESI------SPVVVKIPREQLDLDGGGQSKVGCEQTSEDLKDVQA 1289

  Fly   135 QINLNEIKI-----EFPEADL------------------TIADVLEDQEEQDFLP----DDCISK 172
            ..||...:|     ..||..|                  ||..:  |.:.|....    |..|.:
  Rat  1290 NSNLESKEILMNSQHEPEVILEEDAPASIGTAENNDAYETIISI--DDKGQTMYSFGRFDSSIIR 1352

  Fly   173 EGAEDPEVLEKKPPTLKRKVSGRSRGRRRVQLAERPNTSCLPKIQKSQEFNDYIREHYKVQCHIC 237
            ...||.|::|:  |.....|:|.       :::|.|...|...::|.:.......|..:::|..|
  Rat  1353 IKTEDGELVEQ--PEEGLMVTGG-------KVSELPLKDCAQGLKKKKVEGSSFGESTRIRCDDC 1408

  Fly   238 NLPMEDFSEMLAHVRREH---KQRGYAMCCNRKFLKRGVL------VDHLRRHQD-----PE--- 285
            ....:..|.:..|:..:|   ::..:.:.|.:.|.....|      ..|:|..|.     ||
  Rat  1409 GFLADGLSGLNVHIAMKHPTKEKHFHCLLCGKSFYTESNLHQHLASAGHMRNEQASVEELPEGGA 1473

  Fly   286 TFKCSICGRVMGHRRSLELHMR-MHE----------IKSRGRLYR---------CEQCSKAFYS- 329
            ||||..|.......::|.||:: .||          ::...::.|         |:.|.|...|
  Rat  1474 TFKCVKCTEPFDSEQNLFLHIKGQHEELLREVNKYIVEDTEQINREREENQGNVCKYCGKMCRSS 1538

  Fly   330 -AVVYERHKLTHIPREQWKVPCTHCEKTYPSQYTMQQHVKLVHLNLYAKICDVCGKSIRGREALA 393
             ::.:..|..||...:.:|  |..|..........:.|||. ||.:....|.|||.:.    .:.
  Rat  1539 NSMAFLAHIRTHTGSKPFK--CKICHFATAQLGDARNHVKR-HLGMREYKCHVCGVAF----VMK 1596

  Fly   394 RHMEEH------TGGP-QAAIKCHLCDSMLTTKYGLARHIKMMHTAENLQPMQCEF--CLKICPS 449
            :|:..|      .|.| :....|||||...|.|:.|..|:| :||.|  :|.:|.:  |.....:
  Rat  1597 KHLNTHLLGKHGVGTPKERKFTCHLCDRSFTEKWALNNHVK-LHTGE--KPFKCTWPTCHYSFLT 1658

  Fly   450 LQAHQHHIKYTHNTARSHQCPMCEKAFKRPNELKEHMTTHTGEVLYTCPHCPQTFNSNANMHAHR 514
            ..|.:.|.: ||...:|..|.:|..|....:.|.:|...||||..:.|..|  .|.|....|..|
  Rat  1659 ASAMKDHYR-THTGEKSFLCDLCGFAGGTRHALTKHRRQHTGEKPFKCDEC--NFASTTQSHLTR 1720

  Fly   515 -KKVHRKE------WEENRHKRLNRSRK 535
             |:||..|      |.:.|.......||
  Rat  1721 HKRVHTGEKPYRCPWCDYRSNCAENIRK 1748

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.