DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8388 and Traf4

DIOPT Version :9

Sequence 1:	NP_611075.1	Gene:	CG8388 / 36763	FlyBaseID:	FBgn0034062	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001100487.1	Gene:	Traf4 / 303285	RGDID:	1306708	Length:	470	Species:	Rattus norvegicus

Alignment Length:	413	Identity:	90/413 - (21%)
Similarity:	139/413 - (33%)	Gaps:	166/413 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 KVQCHICNLPMEDFSEMLAHVRREHKQ---RGYAMC--CNRKFLKRGVL--------VDHLRRHQ 282
            ::.|.:|..||           ||..|   .|:..|  |.::||..||.        :|:.:.:.
  Rat    15 RLLCPLCGKPM-----------REPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYP 68

  Fly   283 DPETFKCSICGRVMGHRRSLELHMRMHEIKSRGRLYRC----EQCSKAFYSAVVYERHKLTHIPR 343
            |||.                       |::..|...||    |.|.   :|..:  ||...|:..
  Rat    69 DPEL-----------------------EVQVLGLAIRCIHSEEGCR---WSGPL--RHLQGHLNT 105

  Fly   344 EQWK-VPC-THCEKTYPSQYTMQQHVKLVHLNLYAKI----------CDVCGKSIRGREALARHM 396
            ..:. ||| ..|.            .||...:|.|.:          |:.||....| ||    .
  Rat   106 CSFNVVPCPNRCP------------AKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSG-EA----Y 153

  Fly   397 EEHTG-GPQAAIKC-HLCDSMLTTKYGLARHIKMMHTAE---NLQPMQCEFCLK--ICPSLQAHQ 454
            |.|.| .||.::.| :.|.:.:..:. ||:|.    |:|   ..||  |.:|.|  :..::|:||
  Rat   154 ESHEGVCPQESVYCENKCGARMMRRL-LAQHA----TSECPKRTQP--CAYCTKEFVYDTIQSHQ 211

  Fly   455 HHIKYTHNTARSHQCPM----CEKAFKRPNE------LKEHMTTH------TGEVL--------- 494
                        :|||.    |      ||:      .:|.:.||      |..||
  Rat   212 ------------YQCPRLPVPC------PNQCGVGTVAREDLPTHLKDSCSTAFVLCPFKESGCK 258

  Fly   495 YTCP------HCPQTFNSNANMHAHRKKVHRKEWEENRHKRLNRSRKSDTIIAVSV----RKTTE 549
            :.||      |..::...:..|........|:|.:|.|.:....|..||.::...:    |:..|
  Rat   259 HRCPKLAMGRHVEESVKPHLAMMCALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQE 323

  Fly   550 TRQDGGLVPAEAIATTSSPRAEC 572
            .:              :.|..||
  Rat   324 AK--------------AKPNLEC 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8388	NP_611075.1	zf-AD	<21..77	CDD:285071
		C2H2 Zn finger	264..281	CDD:275368	6/24 (25%)
		C2H2 Zn finger	289..309	CDD:275368	0/19 (0%)
		C2H2 Zn finger	320..340	CDD:275368	6/23 (26%)
		C2H2 Zn finger	350..369	CDD:275368	2/19 (11%)
		C2H2 Zn finger	440..461	CDD:275368	6/22 (27%)
		C2H2 Zn finger	469..489	CDD:275368	6/29 (21%)
		C2H2 Zn finger	497..515	CDD:275368	4/23 (17%)
Traf4	NP_001100487.1	mRING-HC-C3HC3D_TRAF4	15..59	CDD:319555	14/54 (26%)
		zf-TRAF	102..156	CDD:280357	16/70 (23%)
		zf-TRAF	210..269	CDD:280357	16/76 (21%)
		MATH_TRAF4	308..463	CDD:239750	5/39 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000