Protein Alignment CG8388 and Zfp335

DIOPT Version :10

• Sequence 1: NP_611075.1
• Gene: CG8388 / 36763
• FlyBaseID: FBgn0034062
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_063139241.1
• Gene: Zfp335 / 259270
• RGDID: 628751
• Length: 1337
• Species: Rattus norvegicus
• Alignment Length: 648
• Identity: 135/648 - (20%)
• Similarity: 221/648 - (34%)
• Gaps: 222/648 - (34%)

  Fly    22 EEADSLGLRCIIEKHFWLQIPDSKRAGYVCGPCWEQLLLFHNFYLNVEQAHKALEQTVLKETSPP 86
            ||.|..||..::|                       :::...|...:.|...:.:.|:|:.....
  Rat   228 EELDLQGLEAMME-----------------------VVVVQQFKCKMCQYRSSTKATLLRHMRER 269

  Fly    87 EVVASALEEHIVKSEHDDSVAAAVKRRRGRPR------KVAQQDAREELKSVLEQINLNEIKIEF 145
            ....:||           :||||...:|||.|      |..:::..||               |.
  Rat   270 HFRPAAL-----------AVAAAAAGKRGRVRKWGTSTKTTEEEGPEE---------------EE 308

  Fly   146 PEADLTIADVLED-QEEQDFLPDDCISKEGAEDP------EVLEKKPPTLK-RKVSGRSRGRRRV 202
            .:.|:..|..::| :|:.|:.|        |||.      .:....|.||: |:..||.|...|:
  Rat   309 EDDDIVDAGAIDDLEEDSDYNP--------AEDEPRGRQLRLQRPTPSTLRPRRRPGRPRKLPRL 365

  Fly   203 QLA-------------------------ERPNTSCLPKIQK------------------------ 218
            :.:                         |.|::|.|..:.|
  Rat   366 ETSDLHDGIGEPLVSSQSTQSPPELQDLEAPSSSDLRALGKVGRGLVETGVSQSDAENAAPSCQD 430

  Fly   219 ------------SQEF--NDYIREHYK-----VQCHICNLPMEDFSEMLAHVRREHKQRGYAMCC 264
                        |:.|  ..|.:.:||     ::.::|.:                        |
  Rat   431 EADVPPRRRGRPSRRFLGKKYRKYYYKSPKPLLRPYLCRI------------------------C 471

  Fly   265 NRKFLKRGVLVDHLRRHQ--DPETFKCSICGRVMGHRRSLELHMRMHEIKSRGRLYRCEQCSKAF 327
            ..:||....|..|:..|:  ||:.|||..|........||:.||..| :.|:.  |:|::||
  Rat   472 GSRFLSHEDLRFHVNSHEAGDPQLFKCLQCSYRSRRWSSLKEHMFNH-VGSKP--YKCDECS--- 530

  Fly   328 YSAVVYE---RHKLTHIPREQWK---------VPCTHCEKTYPSQYTMQQHVKLVHLNLYAKICD 380
            |::|..:   ||...|....:.:         .||..|.:.||.|..:.||:| .|......:||
  Rat   531 YTSVYRKDVIRHAAVHSQDRKKRPDPTPKLSSFPCPVCGRVYPMQKRLTQHMK-THSTEKPHMCD 594

  Fly   381 VCGKSIRGREALARHMEEHTGGPQAAIKCHLCDSMLTTKYGLARHIKMMHTAENLQPMQCEFCLK 445
            .||||.:.|.....|:..|.   ||...               |..|            ||||..
  Rat   595 KCGKSFKKRYTFKMHLLTHI---QAVAN---------------RRFK------------CEFCEF 629

  Fly   446 ICPSLQAHQHHIKYTHNTARSHQCPMCEKAFKRPNELKEHMTT-HTGEVLYTCPHCPQTFNSNAN 509
            :|...:|..:| :.:|.:.:..:|..|.....|.:.|..|:.. |||...:.|.:|..:.....|
  Rat   630 VCEDKKALLNH-QLSHVSDKPFKCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKN 693

  Fly   510 MHAHRKKVHRKEWEE--NRHKRLNRSRKSDTIIAVSVRKTTETRQDGGLVPAEAIATTSSPRA 570
            :..|.:..|...:||  .||.....||:....   |:::..|.:|.....|...: :::.|.|
  Rat   694 LRLHVRCRHANSFEEWGRRHPEEPPSRRRPFF---SLQQIEELKQQHSAAPGPPL-SSAGPEA 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8388	NP_611075.1	zf-AD	3..78	CDD:462262	8/55 (15%)
		C2H2 Zn finger	264..281	CDD:275368	5/16 (31%)
		C2H2 Zn finger	289..309	CDD:275368	6/19 (32%)
		C2H2 Zn finger	320..340	CDD:275368	7/22 (32%)
		C2H2 Zn finger	350..369	CDD:275368	7/18 (39%)
		C2H2 Zn finger	440..461	CDD:275368	7/20 (35%)
		C2H2 Zn finger	469..489	CDD:275368	5/20 (25%)
		C2H2 Zn finger	497..515	CDD:275368	4/17 (24%)
Zfp335	XP_063139241.1	None