Protein Alignment CG8388 and Zfp407

DIOPT Version :10

• Sequence 1: NP_611075.1
• Gene: CG8388 / 36763
• FlyBaseID: FBgn0034062
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001028513.2
• Gene: Zfp407 / 240476
• MGIID: 2685179
• Length: 2246
• Species: Mus musculus
• Alignment Length: 521
• Identity: 128/521 - (24%)
• Similarity: 198/521 - (38%)
• Gaps: 107/521 - (20%)

  Fly   100 SEHDDSVAAAVKRRR-----GRPRKVAQQDAREELKSV-----LEQ----INLNE-----IKIEF 145
            :|...||...:.|.:     |...||..:...|:||.|     ||.    ||..|     ::.:.
Mouse  1252 AESTSSVVMKIPREQLDLDGGGQNKVGCEQTSEDLKDVQANPILENKEILINSQEEAEVILEEDA 1316

  Fly   146 PEADLTI--ADVLE-----DQEEQDFLP----DDCISKEGAEDPEVLEKKPPTLKRKVSGRSRGR 199
            |.::.|.  .||.|     |.:.|....    |..|.:...||.|::| :|........||
Mouse  1317 PTSNGTADSNDVYETIISIDDKGQTMYSFGRFDSSIIRIKTEDGELVE-QPEEGLTATGGR---- 1376

  Fly   200 RRVQLAERPNTSCLPKIQKSQEFNDYIREHYKVQCHICNLPMEDFSEMLAHVRREH---KQRGYA 261
                ::|.|...|...::|.:.......|..:::|..|....:..|.:..|:..:|   ::..:.
Mouse  1377 ----VSELPLKDCAQGLKKKKVEGGSFGESTRIRCDDCGFLADGLSGLNVHIAMKHPTKEKHFHC 1437

  Fly   262 MCCNRKFLKRGVL------VDHLRRHQD-----PE---TFKCSICGRVMGHRRSLELHMR-MHE- 310
            :.|.:.|.....|      ..|:|..|.     ||   ||||..|.......::|.||:: .||
Mouse  1438 LLCGKSFYTESNLHQHLASAGHMRNEQASVEELPEGGATFKCVKCTEPFDSEQNLFLHIKGQHEE 1502

  Fly   311 ---------IKSRGRLYR---------CEQCSKAFYS--AVVYERHKLTHIPREQWKVPCTHCEK 355
                     ::...::.|         |:.|.|...|  ::.:..|..||...:.:|  |..|..
Mouse  1503 LLREVNKYIVEDTEQINREREENQGNVCKYCGKMCRSSNSMAFLAHIRTHTGSKPFK--CKICHF 1565

  Fly   356 TYPSQYTMQQHVKLVHLNLYAKICDVCGKSIRGREALARHMEEH------TGGP-QAAIKCHLCD 413
            ........:.|||. ||.:....|.|||.:.    .:.:|:..|      .|.| :....|||||
Mouse  1566 ATAQLGDARNHVKR-HLGMREYKCHVCGVAF----VMKKHLNTHLLGKHGVGTPKERKFTCHLCD 1625

  Fly   414 SMLTTKYGLARHIKMMHTAENLQPMQCEF--CLKICPSLQAHQHHIKYTHNTARSHQCPMCEKAF 476
            ...|.|:.|..|:| :||.|  :|.:|.:  |.....:..|.:.|.: ||...:|..|.:|..|.
Mouse  1626 RSFTEKWALNNHMK-LHTGE--KPFKCTWPTCHYSFLTASAMKDHYR-THTGEKSFLCDLCGFAG 1686

  Fly   477 KRPNELKEHMTTHTGEVLYTCPHCPQTFNSNANMHAHR-KKVHRKE------WEENRHKRLNRSR 534
            ...:.|.:|...||||..:.|..|  .|.|....|..| |:||..|      |.:.|.......|
Mouse  1687 GTRHALTKHRRQHTGEKPFKCDEC--NFASTTQSHLTRHKRVHTGEKPYRCPWCDYRSNCAENIR 1749

  Fly   535 K 535
            |
Mouse  1750 K 1750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8388	NP_611075.1	zf-AD	3..78	CDD:462262
		C2H2 Zn finger	264..281	CDD:275368	5/22 (23%)
		C2H2 Zn finger	289..309	CDD:275368	5/20 (25%)
		C2H2 Zn finger	320..340	CDD:275368	5/21 (24%)
		C2H2 Zn finger	350..369	CDD:275368	4/18 (22%)
		C2H2 Zn finger	440..461	CDD:275368	4/22 (18%)
		C2H2 Zn finger	469..489	CDD:275368	5/19 (26%)
		C2H2 Zn finger	497..515	CDD:275368	6/18 (33%)
Zfp407	NP_001028513.2	C2H2 Zn finger	180..200	CDD:275368
		C2H2 Zn finger	209..230	CDD:275368
		C2H2 Zn finger	524..552	CDD:275371
		C2H2 Zn finger	553..575	CDD:275371
		C2H2 Zn finger	1407..1436	CDD:275371	5/28 (18%)
		C2H2 Zn finger	1437..1459	CDD:275371	3/21 (14%)
		C2H2 Zn finger	1479..1500	CDD:275371	5/20 (25%)
		C2H2 Zn finger	1530..1552	CDD:275368	5/21 (24%)
		zf-H2C2_2	1548..1569	CDD:463886	6/22 (27%)
		C2H2 Zn finger	1560..1580	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1588..1608	CDD:275368	6/23 (26%)
		zf-C2H2	1619..1641	CDD:395048	10/22 (45%)
		C2H2 Zn finger	1621..1641	CDD:275368	10/20 (50%)
		zf-H2C2_2	1633..1660	CDD:463886	9/29 (31%)
		C2H2 Zn finger	1649..1671	CDD:275368	4/22 (18%)
		C2H2 Zn finger	1679..1699	CDD:275368	5/19 (26%)
		zf-H2C2_2	1691..1716	CDD:463886	10/26 (38%)
		zf-H2C2_5	1705..1729	CDD:404746	9/25 (36%)
		C2H2 Zn finger	1707..1727	CDD:275368	7/21 (33%)
		zf-H2C2_2	1719..1744	CDD:463886	8/24 (33%)
		C2H2 Zn finger	1735..1752	CDD:275368	4/16 (25%)