Protein Alignment CG8388 and Zfp646

DIOPT Version :10

• Sequence 1: NP_611075.1
• Gene: CG8388 / 36763
• FlyBaseID: FBgn0034062
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_766337.2
• Gene: Zfp646 / 233905
• MGIID: 3665412
• Length: 1788
• Species: Mus musculus
• Alignment Length: 438
• Identity: 93/438 - (21%)
• Similarity: 160/438 - (36%)
• Gaps: 117/438 - (26%)

  Fly   146 PEADLTIADVLEDQEEQDFLPDDCISKEGAEDPEVLE-KKPPTLKRKVSGRSRGRRRVQLAERPN 209
            |.|.....|:||.|:          |.||.:..:..| |:.||.......||.|    ||::...
Mouse   292 PRAFRLPRDLLEHQQ----------SHEGLKQEQPWEDKEMPTTNGHADERSWG----QLSKTGM 342

  Fly   210 TSCLPKIQKSQEFNDYIREHYKVQCHICNLPMEDFSEMLAHVRREHKQRGYAMC--CNRKFLKRG 272
            .:...::..|.:..|...|.|:..|                            |  |.|.:...|
Mouse   343 LNGSGELSSSGQLEDGGSEEYRPFC----------------------------CGDCGRTYRHAG 379

  Fly   273 VLVDHLRRHQDPETFKCSICGRVMGHRRSLELHMRMHEIKSRG---------------------- 315
            .|::|.:.|| ...:.||||.:.:.:..:|:.|:|.|....:|
Mouse   380 SLINHRKSHQ-TGIYPCSICSKQLFNAAALKNHIRAHHRPRQGAGEGGQSSVSSTALTSAENTPK 443

  Fly   316 -----------RLYRCEQCSKAFYSAVVYERHKLTHIPREQWKVPCTHCEKTYPSQYTMQQHVKL 369
                       |.|:|.:|.:|:........|:.:|...|   ..|:.|.:.||:...::.||:
Mouse   444 VDEVPTASLDHRPYKCNECGRAYRHRGSLVNHRHSHRTGE---YQCSLCPRKYPNLMALRNHVR- 504

  Fly   370 VHLNLYAKICDVCGKSIRGREALARHMEEHTGGPQAAI---KCHLC--DSMLTTKYGLARHIKMM 429
            ||.....:..|   ....|..:..:..:....|.:||.   :.|.|  :...|:...:
Mouse   505 VHCKATRRSTD---PGTEGSPSPVKKEQHDPVGMEAAFHGDEEHACKREEEATSNPSM------- 559

  Fly   430 HTAENLQPMQCEFCLKICPSLQAHQHHIKYTH------------NTARSHQCPMCEKAFKRPNEL 482
              |:...|..|..|..:...|::.:|| ..||            :..|:..|..|.|:::....|
Mouse   560 --ADRTVPQVCSICGMLFEDLKSLEHH-SVTHREGEKSRTDSTVSPTRTFACQDCGKSYRHSGSL 621

  Fly   483 KEHMTTH-TGEVLYTCPHCPQTFNSNANMHAHRKKVHRKEWEENRHKR 529
            ..|..|| ||:  ::|..|.:.|::.|.|.:|.:: |.::|...|.|:
Mouse   622 INHRQTHQTGD--FSCGACAKHFHTMAAMKSHLRR-HSRQWNRRRQKQ 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8388	NP_611075.1	zf-AD	3..78	CDD:462262
		C2H2 Zn finger	264..281	CDD:275368	5/16 (31%)
		C2H2 Zn finger	289..309	CDD:275368	7/19 (37%)
		C2H2 Zn finger	320..340	CDD:275368	4/19 (21%)
		C2H2 Zn finger	350..369	CDD:275368	6/18 (33%)
		C2H2 Zn finger	440..461	CDD:275368	5/20 (25%)
		C2H2 Zn finger	469..489	CDD:275368	5/19 (26%)
		C2H2 Zn finger	497..515	CDD:275368	6/17 (35%)
Zfp646	NP_766337.2	C2H2 Zn finger	10..31	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	28..48
		C2H2 Zn finger	69..89	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..196
		C2H2 Zn finger	233..253	CDD:275368
		C2H2 Zn finger	260..280	CDD:275368
		C2H2 Zn finger	288..308	CDD:275368	6/25 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..360		14/67 (21%)
		C2H2 Zn finger	368..388	CDD:275368	6/19 (32%)
		C2H2 Zn finger	395..415	CDD:275368	7/19 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	416..449		1/32 (3%)
		C2H2 Zn finger	459..479	CDD:275368	4/19 (21%)
		C2H2 Zn finger	486..506	CDD:275368	6/20 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	509..531		2/24 (8%)
		C2H2 Zn finger	568..588	CDD:275368	5/20 (25%)
		C2H2 Zn finger	608..628	CDD:275368	5/19 (26%)
		C2H2 Zn finger	635..655	CDD:275368	6/20 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	651..712		5/17 (29%)
		C2H2 Zn finger	808..828	CDD:275368
		C2H2 Zn finger	835..855	CDD:275368
		C2H2 Zn finger	868..886	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	889..916
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	956..976
		C2H2 Zn finger	1037..1057	CDD:275368
		C2H2 Zn finger	1064..1084	CDD:275368
		C2H2 Zn finger	1172..1192	CDD:275368
		C2H2 Zn finger	1199..1219	CDD:275368
		C2H2 Zn finger	1227..1247	CDD:275368
		C2H2 Zn finger	1268..1285	CDD:275368
		C2H2 Zn finger	1295..1315	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1351..1386
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1398..1439
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1455..1489
		C2H2 Zn finger	1500..1518	CDD:275368
		C2H2 Zn finger	1526..1544	CDD:275368
		C2H2 Zn finger	1552..1572	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1579..1629
		C2H2 Zn finger	1642..1662	CDD:275368
		C2H2 Zn finger	1669..1689	CDD:275368
		zf-H2C2_2	1681..1706	CDD:463886
		C2H2 Zn finger	1697..1717	CDD:275368
		C2H2 Zn finger	1726..1746	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1744..1788