Protein Alignment CG8388 and LOC1278345

DIOPT Version :10

• Sequence 1: NP_611075.1
• Gene: CG8388 / 36763
• FlyBaseID: FBgn0034062
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_317816.4
• Gene: LOC1278345 / 1278345
• VectorBaseID: AGAMI1_014171
• Length: 559
• Species: Anopheles gambiae
• Alignment Length: 565
• Identity: 139/565 - (24%)
• Similarity: 227/565 - (40%)
• Gaps: 65/565 - (11%)

  Fly     1 MPCFLCTQTVDDAAGNIEFASEEADSLGLRC-IIEKHFWLQI-PDSKRAGYVCGPCWEQLLLFHN 63
            :.|.||..|.|...........||:    .| .:.:|..|.: .|.....::|..||:.:....:
Mosquito    13 LQCRLCLHTADLLISIFGKRGREAE----MCRKLREHLKLTVKEDETLPKHICLKCWDTVEYIDS 73

  Fly    64 FYLNVEQAHKAL------EQTVLKETSPPEVVASALEEHIVKSEHDDSVAAAVKRRRGRPRKVAQ 122
            |...||:....|      |.|.:...:.|.|...  |.:..:.:..|..:....::..:...:..
Mosquito    74 FVRRVERNQSVLVYGERGEITFIVSVAEPPVEID--ETYDFRKDSADPPSYDEAQKTKQATAMYD 136

  Fly   123 QDAREELKSVLEQINLNEIKIEFPEADLTIADVLEDQEEQDFLP--DDCISKEGAEDPEVLEKKP 185
            :...|||..:          ||.|..| |:::  |:....|.||  ||...:..||..|:.|:|.
Mosquito   137 EGEGEELIEI----------IEAPCED-TVSE--EENLVYDLLPLDDDSDERTTAERDELREEKD 188

  Fly   186 PTLKRKVSGRSRGRRRVQLAERPNTSCLPKIQK-------SQEFNDYIREHYKVQCHICN-LPME 242
            |......:..|.......:..|.|....|.:.|       .:|....:..:|.:.|.:|: ....
Mosquito   189 PIGDGATTIVSTTDEEAGILVRVNDYDFPPMIKDGRMIVHGEELEKCLAAYYGLACELCHQRNWA 253

  Fly   243 DFSEMLAHVRREHKQRGYAMCCNRKFLKRGVLVDHLRRHQDPETFKCSICGRVMGHRRSLELHMR 307
            ...|:.||.|..|.:.|:..||.|...|:..:..|:.:|..||.|:|.||.::|...|.|:.||:
Mosquito   254 TIGELFAHHRAAHGREGFVNCCGRTIEKKSQMAMHMAKHVQPEAFECPICKKMMTTPRILKAHMQ 318

  Fly   308 MHEIKSRGRLYRCEQCSKAFYSAVVYERHKLTHIPREQWKVP---CTHCEKTYPSQYTMQQHVKL 369
            .| :....|..:|:.|.:.|........|..||....:.|..   |..|.:.:.|...:.:|:.|
Mosquito   319 NH-LPEEERPLKCDLCPRRFSYVSALLIHASTHREENEGKCAYHLCHSCGRAFRSGDKLAEHIAL 382

  Fly   370 VHL---NLYAKICDVCGKSIRGREALARHMEEHTGGPQAAIKCHLCDSMLTTKYGLARHIKMMHT 431
            .|.   .....:||.|||....:..|..|:..|.......::|..|...|..|..|.:|:
Mosquito   383 SHRTDGTSNCVMCDTCGKKFISKSNLNYHLTTHQPKVLHQVQCEHCGKWLKNKLCLRKHM----- 442

  Fly   432 AENLQPMQ----CEFCLKICPSLQAHQHHIKYTHNTARSHQCPMCEKAFKRPNELKEHMTTHTGE 492
               ||..|    |:.|.....::|:.|:|.:..|...:...||.|.|:||..:.|:||:..|...
Mosquito   443 ---LQHSQVRHACDQCDYTTINVQSLQNHRRVQHTDEKPFVCPTCGKSFKVKSNLREHLAQHRQG 504

  Fly   493 VLYTCPHCPQTFNSNANMHAHRKKVH---------RKEWEENRHK 528
            ..|:|..|.:.|.|.:|.:.|||::|         :||.||:.|:
Mosquito   505 QKYSCEFCSRKFTSKSNYYCHRKRMHPNELELERRKKEQEESAHR 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8388	NP_611075.1	zf-AD	3..78	CDD:462262	19/82 (23%)
		C2H2 Zn finger	264..281	CDD:275368	4/16 (25%)
		C2H2 Zn finger	289..309	CDD:275368	8/19 (42%)
		C2H2 Zn finger	320..340	CDD:275368	4/19 (21%)
		C2H2 Zn finger	350..369	CDD:275368	4/18 (22%)
		C2H2 Zn finger	440..461	CDD:275368	5/20 (25%)
		C2H2 Zn finger	469..489	CDD:275368	9/19 (47%)
		C2H2 Zn finger	497..515	CDD:275368	6/17 (35%)
LOC1278345	XP_317816.4	None