Protein Alignment Pex11ab and PEX11A

DIOPT Version :10

• Sequence 1: NP_611071.1
• Gene: Pex11ab / 36758
• FlyBaseID: FBgn0034058
• Length: 241
• Species: Drosophila melanogaster
• Sequence 2: NP_003838.1
• Gene: PEX11A / 8800
• HGNCID: 8852
• Length: 247
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 80/245 - (32%)
• Similarity: 127/245 - (51%)
• Gaps: 8/245 - (3%)

  Fly     1 MDQLVQLNNQAGGRDKIARLIQYASRAMWDSLESANSNPALVDNFKTVEYILSTFRKLLRFGKCV 65
            ||...:..||..|||::.|..||....:...||.......:|...|.:|..:||.||..|.|..|
Human     1 MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVV 65

  Fly    66 DVFYGALKTIHHPDLNIRVTLTLSKLSQSLFLFADHFLWLARTGLTA-VNAKRWSNIANKYWLFS 129
            .......::||..||..|:.|||:.|::.::...|..||:...|||: :|.::|...|..::.:|
Human    66 HAIQATEQSIHATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYS 130

  Fly   130 IIMNLCRDFYEI-LRVLDLHRSGSKSGISRCRIPASINSPEDFKRLALQSYVL-----MQGHKDI 188
            ::::|.||.||| |::..:....:|...|..:.|...:..|: :...|||::|     ::.|..:
Human   131 LLLSLVRDLYEISLQMKRVTCDRAKKEKSASQDPLWFSVAEE-ETEWLQSFLLLLFRSLKQHPPL 194

  Fly   189 VVDTVKNACDFFIPLTALGYTSLTPRTIGLLGAISSLAGLWALLEPRAKL 238
            ::|||||.||...||..||.....|..|||.|.:||:||:..:..|:.||
Human   195 LLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITVAYPQMKL 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex11ab	NP_611071.1	PEX11	1..232	CDD:398979	77/237 (32%)
PEX11A	NP_003838.1	PEX11	1..237	CDD:398979	77/236 (33%)
		Required for homodimerization, interaction with PEX11G, and peroxisomal localization. /evidence=ECO:0000269|PubMed:20826455	220..239		8/18 (44%)