DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex11 and Pex11a

DIOPT Version :9

Sequence 1:	NP_611071.1	Gene:	Pex11 / 36758	FlyBaseID:	FBgn0034058	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_445939.1	Gene:	Pex11a / 85249	RGDID:	619842	Length:	246	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	78/250 - (31%)
Similarity:	128/250 - (51%)	Gaps:	19/250 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDQLVQLNNQAGGRDKIARLIQYASRAMWDSLESANSNPALVDNFKTVEYILSTFRKLLRFGKCV 65
            ||..:::.||:.|||::.|..|:|...:...|||.....|:|...|.:|..:||.||..|.|..:
  Rat     1 MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKAGKEAVVTKLKNLETSVSTGRKWFRLGNVL 65

  Fly    66 DVFYGALKTIHHPDLNIRVTLTLSKLSQSLFLFADHFLWLARTGLTA-VNAKRWSNIANKYWLFS 129
            .......::|...||..|:.|||:.|::.::...|..||....|||: :|.::|...|.:::.:.
  Rat    66 HAIQATEQSIQATDLVPRLCLTLANLNRVVYYICDTVLWAKSVGLTSGINREKWQMRAARHYYYF 130

  Fly   130 IIMNLCRDFYEILRVLDLHRSGSKSGISRCRIPASINSPEDFKRLA------LQSYVL-----MQ 183
            ::::|.||.||:|    ||.  .:....|.:...|...|..:. :|      |||::|     ::
  Rat   131 LLLSLVRDLYEVL----LHM--GQVARDRAKREKSSGDPPKYS-VANEESEWLQSFLLLLFQSLK 188

  Fly   184 GHKDIVVDTVKNACDFFIPLTALGYTSLTPRTIGLLGAISSLAGLWALLEPRAKL 238
            .:..:.:|||||.||..|||..||........:|..|.:||:|||..::.|:.||
  Rat   189 RNPPLFLDTVKNFCDILIPLNQLGIYKSNLGVVGFGGLVSSVAGLITVVYPQLKL 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex11	NP_611071.1	PEX11	1..232	CDD:283335	75/242 (31%)
Pex11a	NP_445939.1	PEX11	1..237	CDD:283335	75/242 (31%)
Pex11a	NP_445939.1	Required for homodimerization, interaction with PEX11G, and peroxisomal localization. /evidence=ECO:0000250\|UniProtKB:O75192	218..238		7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338866
Domainoid	1	1.000	126	1.000	Domainoid score	I5305
eggNOG	1	0.900	-	-		E1_KOG4186
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I4537
OMA	1	1.010	-	-		QHG49577
OrthoDB	1	1.010	-	-		D1394894at2759
OrthoFinder	1	1.000	-	-		FOG0003074
OrthoInspector	1	1.000	-	-		otm45229
orthoMCL	1	0.900	-	-		OOG6_103414
Panther	1	1.100	-	-	LDO	PTHR12652
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2920
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770