DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pex11 and Pex11a

DIOPT Version :9

Sequence 1:NP_611071.1 Gene:Pex11 / 36758 FlyBaseID:FBgn0034058 Length:241 Species:Drosophila melanogaster
Sequence 2:NP_035198.1 Gene:Pex11a / 18631 MGIID:1338788 Length:246 Species:Mus musculus


Alignment Length:250 Identity:82/250 - (32%)
Similarity:128/250 - (51%) Gaps:19/250 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MDQLVQLNNQAGGRDKIARLIQYASRAMWDSLESANSNPALVDNFKTVEYILSTFRKLLRFGKCV 65
            ||..:::.||:.|||::.|..|:|...:...|||.....|:|...|.:|..:||.||..|.|...
Mouse     1 MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKADKEAVVLKLKRLETSVSTGRKWFRLGNVF 65

  Fly    66 DVFYGALKTIHHPDLNIRVTLTLSKLSQSLFLFADHFLWLARTGLTA-VNAKRWSNIANKYWLFS 129
            .......::|...||..|:.|||:.|::.::...|..||....|||: ||.::|...|.:::.:.
Mouse    66 HAIQATEQSIQAADLAPRLCLTLANLNRVVYYICDTVLWAKSVGLTSGVNREKWQRWAARHYYYF 130

  Fly   130 IIMNLCRDFYEILRVLDLHRSGSKSGISRCRIPASINSPEDFKRLA------LQSYVL-----MQ 183
            ::::|.||.||||..:      .:....|.:...|...|..:. :|      |||::|     ::
Mouse   131 LLLSLVRDLYEILLQM------GQVARDRAKREKSSRDPPKYS-VANEETEWLQSFLLLLFQSLK 188

  Fly   184 GHKDIVVDTVKNACDFFIPLTALGYTSLTPRTIGLLGAISSLAGLWALLEPRAKL 238
            .|..:::|||||.||..|||..||........:||.|.|||||||..::.|:.||
Mouse   189 RHPPLLLDTVKNFCDILIPLNQLGIYKSNLGVVGLGGLISSLAGLLTVVYPQLKL 243

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pex11NP_611071.1 PEX11 1..232 CDD:283335 79/242 (33%)
Pex11aNP_035198.1 PEX11 1..237 CDD:283335 79/242 (33%)
Required for homodimerization, interaction with PEX11G, and peroxisomal localization. /evidence=ECO:0000250|UniProtKB:O75192 218..238 10/19 (53%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167835264
Domainoid 1 1.000 128 1.000 Domainoid score I5303
eggNOG 1 0.900 - - E1_KOG4186
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 133 1.000 Inparanoid score I4585
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG49577
OrthoDB 1 1.010 - - D1394894at2759
OrthoFinder 1 1.000 - - FOG0003074
OrthoInspector 1 1.000 - - otm43159
orthoMCL 1 0.900 - - OOG6_103414
Panther 1 1.100 - - LDO PTHR12652
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1731
SonicParanoid 1 1.000 - - X2920
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1514.800

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