Protein Alignment CG8314 and ZDHHC18

DIOPT Version :10

• Sequence 1: NP_611070.1
• Gene: CG8314 / 36757
• FlyBaseID: FBgn0034057
• Length: 293
• Species: Drosophila melanogaster
• Sequence 2: NP_115659.1
• Gene: ZDHHC18 / 84243
• HGNCID: 20712
• Length: 388
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 81/301 - (26%)
• Similarity: 124/301 - (41%)
• Gaps: 77/301 - (25%)

  Fly     5 YSALSPGGSGGFGGVDQHNRCCGNKAWCV-----KDICG----------------IVCVIMTWLL 48
            :|:...|...|.|.:.:..|    :.|.|     :..||                ::.:..|.|.
Human    48 WSSSGSGSGSGSGSLGRRPR----RKWEVFPGRNRFYCGGRLMLAGHGGVFALTLLLILTTTGLF 108

  Fly    49 ILF-AEFVVMRLIL-LPSNYTVFSTINMIIFQALAFLAFASHIRTMLSDPGAVPRGN-----ATK 106
            .:| ..::..:|.| :|           ||...|.|...:..::|..:|||.:||..     |.:
Human   109 FVFDCPYLARKLTLAIP-----------IIAAILFFFVMSCLLQTSFTDPGILPRATVCEAAALE 162

  Fly   107 EMIEQMG---YR----------EGQM--FYKCPKCCSIKPERAHHCSVCQRCIRKMDHHCPWVNN 156
            :.|:..|   ||          .|||  ...|..|...:|.|..|||||..|:.:.|||||||.|
Human   163 KQIDNTGSSTYRPPPRTREVLINGQMVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGN 227

  Fly   157 CVGENNQKYFVLFTFYIASISVHTLFL---VLTQFAECVKNDWRTCSPYSPPATIFLLLFLTFEG 218
            |||..|.::|..|   |.|:|..|.|:   |:|......:......:....||:: |.|.:.|
Human   228 CVGRRNYRFFYAF---ILSLSFLTAFIFACVVTHLTLRAQGSNFLSTLKETPASV-LELVICF-- 286

  Fly   219 LMFGIFTIIMLA---TQLTAILNDQTGIEQLKKEEARWAKK 256
              |.|::|:.|:   |.|.|  ::.|..|.:|   ..|:.|
Human   287 --FSIWSILGLSGFHTYLVA--SNLTTNEDIK---GSWSSK 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8314	NP_611070.1	DHHC	122..249	CDD:396215	46/132 (35%)
ZDHHC18	NP_115659.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..67		4/18 (22%)
		DHHC	191..314	CDD:396215	45/132 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..388