Protein Alignment CG8314 and Zdhhc1

DIOPT Version :10

• Sequence 1: NP_611070.1
• Gene: CG8314 / 36757
• FlyBaseID: FBgn0034057
• Length: 293
• Species: Drosophila melanogaster
• Sequence 2: NP_780369.1
• Gene: Zdhhc1 / 70796
• MGIID: 1918046
• Length: 484
• Species: Mus musculus
• Alignment Length: 307
• Identity: 79/307 - (25%)
• Similarity: 118/307 - (38%)
• Gaps: 93/307 - (30%)

  Fly    43 IMTWLLILFAEFVVMRLIL-------LPSNYTVFSTINMIIFQALAFLAFASHIRTMLS----DP 96
            |:.|||.||...:...:::       :|:.|.....|            ||.|:...|:    ||
Mouse    50 IVAWLLYLFFAVIGFGVLVPLLPHHWVPAGYACMGAI------------FAGHLVVHLTAVSIDP 102

  Fly    97 -----------GAVPRGNATK--EMIEQMGYREGQMFYKCPKCCSIKPERAHHCSVCQRCIRKMD 148
                       |.:|..|.::  .:||.:         .|..|......|:.|||.|.:|:...|
Mouse   103 ADANVRDKSYSGPLPIFNRSQHAHVIEDL---------HCNLCDVDVSARSKHCSACNKCVCGFD 158

  Fly   149 HHCPWVNNCVGENNQKYFVLFTFYIASISVHTLFLVL------------------TQFAECVKND 195
            |||.|:||||||.|.:   ||...:||..:..|.|||                  .|..|.:||.
Mouse   159 HHCKWLNNCVGERNYR---LFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNQHFEVLKNH 220

  Fly   196 ---WRTCSPYSP-----PATIFLLLFLTFEGL----MFG---IFTIIMLATQLTAILNDQTGIEQ 245
               |....|.:|     ||.:.|...|...||    :.|   .|.|.::..:||..   :..::.
Mouse   221 TDVWFVFLPAAPVETQAPAILALAALLILLGLLSTALLGHLLCFHIYLMWHKLTTY---EYIVQH 282

  Fly   246 LKKEEARWAKKS------RLKSIQSVFGRFSLAWFSPF-TEPSCRTR 285
            ...:||:...|.      :::|||.:  .|.:..||.. .|||.:.|
Mouse   283 RPAQEAKETHKELESCPRKVRSIQEM--EFYMRTFSHVRPEPSGQAR 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8314	NP_611070.1	DHHC	122..249	CDD:396215	46/159 (29%)
Zdhhc1	NP_780369.1	Mediates interaction with STING1. /evidence=ECO:0000250|UniProtKB:Q8WTX9	1..268		64/241 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38
		DHHC	126..281	CDD:396215	48/169 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..415
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	444..484