DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8314 and Zdhhc3

DIOPT Version :9

Sequence 1:	NP_611070.1	Gene:	CG8314 / 36757	FlyBaseID:	FBgn0034057	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_001359467.1	Gene:	Zdhhc3 / 69035	MGIID:	1926134	Length:	332	Species:	Mus musculus

Alignment Length:	272	Identity:	154/272 - (56%)
Similarity:	191/272 - (70%)	Gaps:	15/272 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PGGSGGFGGVDQHNRCCGNKAWCVKDICGIVCVIMTWLLILFAEFVVMRLILLPSNYTVFSTINM 74
            ||.:|..              |.::|.|||.|.|:||.|:|:|||||:.::|:||....:|.||.
Mouse    30 PGPAGAM--------------WFIRDGCGIACAIVTWFLVLYAEFVVLFVMLVPSRDYAYSIING 80

  Fly    75 IIFQALAFLAFASHIRTMLSDPGAVPRGNATKEMIEQMGYREGQMFYKCPKCCSIKPERAHHCSV 139
            |:|..|||||.|||.|.||:||||||:||||||.||.:..:.||:.|||||||||||:|||||||
Mouse    81 IVFNLLAFLALASHCRAMLTDPGAVPKGNATKEFIESLQLKPGQVVYKCPKCCSIKPDRAHHCSV 145

  Fly   140 CQRCIRKMDHHCPWVNNCVGENNQKYFVLFTFYIASISVHTLFLVLTQFAECVKNDWRTCSPYSP 204
            |:|||||||||||||||||||||||||||||.|||.||:|.|.:|...|..|.:.||..||.:||
Mouse   146 CKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFEEDWTKCSSFSP 210

  Fly   205 PATIFLLLFLTFEGLMFGIFTIIMLATQLTAILNDQTGIEQLKKEEARWAKKSRLKSIQSVF-GR 268
            |.|:.||:.|.||.|:|.|||.:|..||:.:|..|:||||:|::.:....:....||:|..| |.
Mouse   211 PTTVILLILLCFEALLFLIFTSVMFGTQVHSICTDETGIERLQRTKQPREQSGSWKSVQEAFGGN 275

  Fly   269 FSLAWFSPFTEP 280
            |||.||:|||.|
Mouse   276 FSLNWFNPFTRP 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8314	NP_611070.1	DHHC	122..249	CDD:396215	85/126 (67%)
Zdhhc3	NP_001359467.1	DHHC	128..253	CDD:366691	84/124 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850616
Domainoid	1	1.000	201	1.000	Domainoid score	I3009
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9582
Inparanoid	1	1.050	347	1.000	Inparanoid score	I2288
Isobase	1	0.950	-	0	Normalized mean entropy	S1626
OMA	1	1.010	-	-		QHG49015
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	1	1.000	-	-		FOG0001671
OrthoInspector	1	1.000	-	-		otm43062
orthoMCL	1	0.900	-	-		OOG6_104274
Panther	1	1.100	-	-	LDO	PTHR22883
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4176
SonicParanoid	1	1.000	-	-		X2063
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750