DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8314 and zdhhc23b

DIOPT Version :9

Sequence 1:	NP_611070.1	Gene:	CG8314 / 36757	FlyBaseID:	FBgn0034057	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_001003757.1	Gene:	zdhhc23b / 445301	ZFINID:	ZDB-GENE-040808-13	Length:	425	Species:	Danio rerio

Alignment Length:	211	Identity:	57/211 - (27%)
Similarity:	86/211 - (40%)	Gaps:	63/211 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 DPGAVPRGNATKEMIEQMGYREGQMFYKCPKCCSIKPERAHHCSVCQRCIRKMDHHCPWVNNCVG 159
            :||       |:|  |:.|.::...   |..|..::|.||.||.:|..|:.::||||.|:|:|||
Zfish   233 EPG-------TEE--EEEGVQKRNW---CAVCKVVRPRRAGHCRICGVCVLRLDHHCVWINSCVG 285

  Fly   160 ENNQKYFVLFTFYIASISVHTLFLVLTQFAECVKNDWR---------------------TCSPYS 203
            ..|.:.|:|...:....|:..:.|||..    |..|.|                     ||:.||
Zfish   286 LANHRTFLLTLLFFLLTSIFGISLVLAS----VCPDQRVLTALFYCPDVYSQYSSALCFTCAWYS 346

  Fly   204 PPATIFLLLFLTFEGLMFGIFTIIMLATQLTAILNDQTGIEQLKKEEARWA--KKSRLKSIQSVF 266
            ...|..||..|                  |..|||....:.:   .|||.|  :||..:.:..:.
Zfish   347 SIVTGGLLHLL------------------LLQILNISLNVTE---REARLALREKSAQRRLWGLI 390

  Fly   267 ---GRFSLAWFSPFTE 279
               |.:|..::|.:||
Zfish   391 VHTGHYSRGFWSNWTE 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8314	NP_611070.1	DHHC	122..249	CDD:396215	40/147 (27%)
zdhhc23b	NP_001003757.1	7TMR-DISM_7TM	<62..179	CDD:284997
zdhhc23b	NP_001003757.1	zf-DHHC	<244..>350	CDD:303066	32/112 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810