DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8314 and ZDHHC5

DIOPT Version :9

Sequence 1:	NP_611070.1	Gene:	CG8314 / 36757	FlyBaseID:	FBgn0034057	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_056272.2	Gene:	ZDHHC5 / 25921	HGNCID:	18472	Length:	715	Species:	Homo sapiens

Alignment Length:	229	Identity:	62/229 - (27%)
Similarity:	87/229 - (37%)	Gaps:	62/229 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 IFQALAFL-AFASHIRTMLSDPGAVPRGNATKE-----------MIEQMGYREGQMFYKCPKCCS 128
            |:.|:.|| ..|:.......|||..||....::           .:|..|.:....:  |..|..
Human    49 IYNAIMFLFVLANFSMATFMDPGIFPRAEEDEDKEDDFRAPLYKTVEIKGIQVRMKW--CATCRF 111

  Fly   129 IKPERAHHCSVCQRCIRKMDHHCPWVNNCVGENNQKYFVLF----TFYIASISVHTLFLVLTQFA 189
            .:|.|..|||||..|:.:.||||||||||:|..|.:||.||    |.:|..:....|..||....
Human   112 YRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLYVLYHIE 176

  Fly   190 ECVKNDWRTCSPYSPPATIFLLLFLTFEGLMF----GI--FTIIMLATQLTAILNDQTGIEQLKK 248
            |           .|...|...:..:...||.|    |:  |.::::|...|.  |:|
Human   177 E-----------LSGVRTAVTMAVMCVAGLFFIPVAGLTGFHVVLVARGRTT--NEQ-------- 220

  Fly   249 EEARWAKKSRLKSIQSVFGRFSLAWFSPFTEPSC 282
                            |.|:|. ...:|||...|
Human   221 ----------------VTGKFR-GGVNPFTNGCC 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8314	NP_611070.1	DHHC	122..249	CDD:396215	43/136 (32%)
ZDHHC5	NP_056272.2	DHHC	99..224	CDD:366691	44/163 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..715
		DUF4671	594..>704	CDD:374041
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810