DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8314 and Zdhhc19

DIOPT Version :9

Sequence 1:	NP_611070.1	Gene:	CG8314 / 36757	FlyBaseID:	FBgn0034057	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_955013.1	Gene:	Zdhhc19 / 245308	MGIID:	2682948	Length:	347	Species:	Mus musculus

Alignment Length:	281	Identity:	71/281 - (25%)
Similarity:	121/281 - (43%)	Gaps:	51/281 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 VKDICGIVCVIMTWL-LILFAEFVVMRLILL-------PSNYTV------FSTINMIIFQALAFL 83
            ||:...:..:.::|. ..:||.|.|..|:.|       |..:.|      |..|...:|    .|
Mouse    11 VKEPQQLPSIPLSWFPSSVFAAFNVTLLLFLSGLFFGFPCRWLVQNGEWAFPAITGPLF----IL 71

  Fly    84 AFASHIRTMLSDPGAVPRGNATKEMIEQMGYREGQMFYK---CPKCCSIKPERAHHCSVCQRCIR 145
            .|.|.:....||||.:.||:..::.:.....|..|..::   ||||...:|.|.:||..|..|:.
Mouse    72 TFFSLVSLNFSDPGILHRGSTKEDPMTVHVVRVNQRAFRLEWCPKCLFHRPPRTYHCPWCNICVE 136

  Fly   146 KMDHHCPWVNNCVGENNQKYFVLFTFYIASISVHTLFLVLTQFAECVKNDWRTCS-PYSPPATIF 209
            ..||||.|||||:|..|   |.||...:.|:.:::..|::|    |:...:||.. |:|....:.
Mouse   137 DFDHHCKWVNNCIGHRN---FRLFMLLVLSLCLYSGALLVT----CLTFLFRTRHLPFSLDKGMA 194

  Fly   210 LLLFLTFEGLMFGIFTIIMLATQLTAILNDQTGIEQLKKEEARWAKKSRLKSIQSVFGR-----F 269
            :|:.:...|.:..:|.::::...            .:.:.|:.:..|.|.....:.|.:     :
Mouse   195 ILVAVPAAGFLIPLFLLLLIQAL------------SVSRAESSYESKCRYHPEYNPFDQGFAKNW 247

  Fly   270 SLAWFSP-----FTEPSCRTR 285
            .||.|:|     .:|..|..|
Mouse   248 YLAMFAPLGPNYMSEVVCLQR 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8314	NP_611070.1	DHHC	122..249	CDD:396215	35/130 (27%)
Zdhhc19	NP_955013.1	DHHC	109..>181	CDD:366691	28/78 (36%)
Zdhhc19	NP_955013.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..347
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810