DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8314 and Zdhhc14

DIOPT Version :9

Sequence 1:	NP_611070.1	Gene:	CG8314 / 36757	FlyBaseID:	FBgn0034057	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_666185.3	Gene:	Zdhhc14 / 224454	MGIID:	2653229	Length:	489	Species:	Mus musculus

Alignment Length:	302	Identity:	75/302 - (24%)
Similarity:	123/302 - (40%)	Gaps:	72/302 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YSALSPGGSGGFGGVDQHNRCCGNKAWCV-----KDIC----------GIVCVIMTWLLILFAEF 54
            ||.:|...|.......:..:....:.|.|     |..|          |:..:.:..:|:....|
Mouse    14 YSQISTHSSSPMESPHKKKKIAARRKWEVFPGRNKFFCNGRIMMARQTGVFYLTLILILVTSGLF 78

  Fly    55 VVMRLILLPSNYT-VFSTINMIIFQALAFLAFASHIRTMLSDPGAVPRG--NATKEMIEQM---- 112
            .......|....| ....:..|:|    |....:.:||..||||.:||.  :...::..|:
Mouse    79 FAFDCRYLAEKITPAIPVVGGILF----FFVMGTLLRTSFSDPGVLPRATPDEAADLERQIDIAN 139

  Fly   113 -----GYR----------EGQ---MFYKCPKCCSIKPERAHHCSVCQRCIRKMDHHCPWVNNCVG 159
                 |||          .||   :.| |..|...:|.||.|||:|..|:.:.|||||||.||||
Mouse   140 GTSSGGYRPPPRTKEVVINGQTVKLKY-CFTCKIFRPPRASHCSLCDNCVEQFDHHCPWVGNCVG 203

  Fly   160 ENNQKYFVLFTFYIASISVHTLFLVLTQ---------FAECVKNDWRTCSPYSPPATIFLLLFLT 215
            :.|.::|.:|...::.::|.....|:|.         |.:.:|:.         ||:: |...:.
Mouse   204 KRNYRFFYMFILSLSFLTVFIFAFVITHVIHRSQQKGFLDALKDS---------PASV-LEAVIC 258

  Fly   216 FEGLMFGIFTIIMLATQLTAIL-NDQTGIEQLKKEEARWAKK 256
            |    |.:::||.|:...|.:: ::||..|.:|   ..|:.|
Mouse   259 F----FSVWSIIGLSGFHTYLISSNQTTNEDIK---GSWSNK 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8314	NP_611070.1	DHHC	122..249	CDD:396215	42/136 (31%)
Zdhhc14	NP_666185.3	zf-DHHC	164..289	CDD:307600	43/142 (30%)
Zdhhc14	NP_666185.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	434..454
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810