DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8314 and dhhc-14

DIOPT Version :9

Sequence 1:	NP_611070.1	Gene:	CG8314 / 36757	FlyBaseID:	FBgn0034057	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_001024514.2	Gene:	dhhc-14 / 181109	WormBaseID:	WBGene00044071	Length:	565	Species:	Caenorhabditis elegans

Alignment Length:	266	Identity:	60/266 - (22%)
Similarity:	95/266 - (35%)	Gaps:	80/266 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 MTWLLILFAEFVV------------MRLI----------LLPSNYTVFSTINMII---------- 76
            ||:||..:...::            |.||          |||...|:...|.|::
Worm   282 MTYLLFKYLPLIIATFSTLISCIFLMVLIRFDYHDPTYKLLPYGVTIAEAILMVLSWSAYAHWYV 346

  Fly    77 -----------FQALAFLAFASHIRTMLSDPGAVPRGNATKEMI---EQMGYREGQMFYKCPKCC 127
                       ..||||..|  .|.|:  |||.|.......::.   .:.|.:..|.:  |..|.
Worm   347 PWWAQMLFVLSVLALAFTLF--RIGTL--DPGVVRAAKNCHQLFVNEAEAGIQHQQKY--CFTCF 405

  Fly   128 SIKPERAHHCSVCQRCIRKMDHHCPWVNNCVGENNQKYFVLF--------TFYIASISVHTLFLV 184
            ..|.:...||:||..|:...||||||:|:||...|.:.|::|        ..|..:.|.:.|..:
Worm   406 IRKMDHTKHCAVCGFCVNNFDHHCPWLNSCVTRRNMREFIMFVISVSVSSAIYCMATSHYALLQI 470

  Fly   185 ----LTQFAECVKNDWRTCSPYSPPATIFLLLFLTFEGLMFGIFTIIMLATQLTAILNDQTGIEQ 245
                |.:|.|               ...||::.:.... |..:...::...|:..|....|..::
Worm   471 EDHGLEEFLE---------------TDAFLMITIILSA-MHALMLAVLFCVQMNQISQGVTTNDR 519

  Fly   246 LKKEEA 251
            :|...|
Worm   520 IKARRA 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8314	NP_611070.1	DHHC	122..249	CDD:396215	33/138 (24%)
dhhc-14	NP_001024514.2	ANK	19..143	CDD:238125
		Ank_2	30..120	CDD:289560
		ANK repeat	55..87	CDD:293786
		ANK repeat	89..120	CDD:293786
		Ank_2	94..222	CDD:289560
		ANK	117..244	CDD:238125
		ANK repeat	190..222	CDD:293786
		PulO	<261..>367	CDD:224900	18/86 (21%)
		zf-DHHC	394..521	CDD:279823	33/144 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910