DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8314 and ZDHHC19

DIOPT Version :9

Sequence 1:	NP_611070.1	Gene:	CG8314 / 36757	FlyBaseID:	FBgn0034057	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_001034706.1	Gene:	ZDHHC19 / 131540	HGNCID:	20713	Length:	309	Species:	Homo sapiens

Alignment Length:	219	Identity:	58/219 - (26%)
Similarity:	96/219 - (43%)	Gaps:	44/219 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 VVMRLILLPSNYTVFSTINMIIFQALAF------------------------LAFASHIRTMLSD 95
            :|.|...|||.:..|:.:.::.|..|.|                        |.|.|.:....||
Human    19 LVPRPWFLPSLFAAFNVVLLVFFSGLFFAFPCRWLAQNGEWAFPVITGSLFVLTFFSLVSLNFSD 83

  Fly    96 PGAVPRGNATKE--MIEQMGYREGQMFYK-CPKCCSIKPERAHHCSVCQRCIRKMDHHCPWVNNC 157
            ||.:.:|:|.:.  .:..:....|....: |||||..:|.|.:||..|..|:...||||.|||||
Human    84 PGILHQGSAEQGPLTVHVVWVNHGAFRLQWCPKCCFHRPPRTYHCPWCNICVEDFDHHCKWVNNC 148

  Fly   158 VGENNQKYFVLFTFYI-----ASISVHTLFLVLTQFAECVKNDWRTCSPYSPPATIFLLLFLTFE 217
            :|..|.::|:|....:     |.:....:|||.|           |..|:|....|.:::.::..
Human   149 IGHRNFRFFMLLVLSLCLYSGAMLVTCLIFLVRT-----------THLPFSTDKAIAIVVAVSAA 202

  Fly   218 GLMFGIFTIIMLATQLTAILNDQT 241
            ||:..: ::::|...|:....|:|
Human   203 GLLVPL-SLLLLIQALSVSSADRT 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8314	NP_611070.1	DHHC	122..249	CDD:396215	39/126 (31%)
ZDHHC19	NP_001034706.1	DHHC	109..>181	CDD:366691	27/71 (38%)
ZDHHC19	NP_001034706.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..309
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810