DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8314 and zdhhc17

DIOPT Version :9

Sequence 1:	NP_611070.1	Gene:	CG8314 / 36757	FlyBaseID:	FBgn0034057	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_001121854.1	Gene:	zdhhc17 / 100148543	ZFINID:	ZDB-GENE-070424-194	Length:	620	Species:	Danio rerio

Alignment Length:	312	Identity:	80/312 - (25%)
Similarity:	124/312 - (39%)	Gaps:	95/312 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 AWCVKDICGIVCVIMTWLLILFAEFVVMRLILLPS--NYTVFSTINMIIFQALAF---------- 82
            :|.:|   |::..:| ||::.|         |..|  ::::.|.:.:.|:.|..|
Zfish   315 SWLIK---GVMYAVM-WLVVQF---------LSKSFFDHSMHSALPLGIYLATKFWMYITWFYWF 366

  Fly    83 ---LAFAS-HIRTML--------------SDPGAVPRGNATKEM----IEQMGYREGQMFYKCPK 125
               |.|.: |:..:|              ||||.:......|:.    :.:.|..:..:|  |..
Zfish   367 WNDLPFVTIHLPFLLNSLALFYNFGKSWKSDPGIIKASEEQKKKTIVELAETGSLDLSIF--CST 429

  Fly   126 CCSIKPERAHHCSVCQRCIRKMDHHCPWVNNCVGENNQKYFVLFTFYI----------------- 173
            |...||.|:.||:||.|||.|.|||||||.||||..|.:||:.:.|::
Zfish   430 CLIRKPIRSKHCAVCNRCIAKFDHHCPWVGNCVGSGNHRYFMGYLFFLLCMICWMMYGCICYWRI 494

  Fly   174 ---ASISVHTLFLVLTQFAECVKNDWRTCSPYSPPATIFLLLFLTFEGLMF---GIFTIIMLATQ 232
               .|.:....::.:||.|        ||||:         :|..|...:|   .:..:||....
Zfish   495 HCATSYTKDGFWIYITQIA--------TCSPW---------MFWMFLNSVFHFMWVAVLIMCQLY 542

  Fly   233 LTAILNDQTGIEQLKKEEARWAK--KSRLKSIQSVFGRFSLAWFSPFTEPSC 282
            ..|:|    ||...::..||..|  |....||:|.|....:.....|.|..|
Zfish   543 QIAVL----GITTNERMNARRYKHFKVTATSIESPFNHGCMRNLIDFFELRC 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8314	NP_611070.1	DHHC	122..249	CDD:396215	45/149 (30%)
zdhhc17	NP_001121854.1	PHA02874	<59..>253	CDD:165205
		ANK repeat	77..108	CDD:293786
		ANK 1. /evidence=ECO:0000255	77..106
		ANK repeat	110..142	CDD:293786
		ANK 2. /evidence=ECO:0000255	111..140
		ANK repeat	144..175	CDD:293786
		ANK 3. /evidence=ECO:0000255	144..173
		Ank_2	150..243	CDD:403870
		ANK repeat	177..209	CDD:293786
		ANK 4. /evidence=ECO:0000255	177..207
		ANK repeat	212..243	CDD:293786
		ANK 5. /evidence=ECO:0000255	212..241
		ANK 6. /evidence=ECO:0000255	245..274
		DHHC	426..556	CDD:396215	46/152 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810