DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Strn-Mlck and hmcn1

DIOPT Version :9

Sequence 1:	NP_001261019.1	Gene:	Strn-Mlck / 36753	FlyBaseID:	FBgn0265045	Length:	8255	Species:	Drosophila melanogaster
Sequence 2:	XP_005160777.1	Gene:	hmcn1 / 559150	ZFINID:	ZDB-GENE-041014-322	Length:	5623	Species:	Danio rerio

Alignment Length:	3914	Identity:	779/3914 - (19%)
Similarity:	1309/3914 - (33%)	Gaps:	1303/3914 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  4998 TDEKAEESRKEEVKDSEAKPKKAKVLEKKSIEEEKLEDKKEKQTESAI---DEKSQKAEVSETVS 5059
            |:.....|||.:: ....:||.:      .:.|..:.|..||..|.::   |:.:...||.....
Zfish  1046 TNAAGYSSRKVQL-TVYVRPKLS------GVGEADIHDNSEKLLEMSVIVGDDITLPCEVESVPP 1103

  Fly  5060 EKITDEKAQESQKKEVKDSEAKPKKAKILEKKSIEIEKLDEKKEKQTETKVATDTK--------- 5115
            ..||..|    .|:.:  |...|:..: |...|:.|          |:|:| ||:.
Zfish  1104 PIITWAK----DKQLI--SPFSPRHIQ-LPSGSMRI----------TDTRV-TDSGMYLCVATNI 1150

  Fly  5116 ----SQTVEVSEIVLEKISEEKAEESQKVEL--------------KDSEAKSKKAKVLEKKSTLK 5162
                ||||::|.:|...||  ....:.||::              :.|.:..|...||:..|..:
Zfish  1151 AGNFSQTVKLSVLVPPSIS--AGPRAMKVQIGHAIDLPCVTQGVPEPSVSWLKDGTVLQDGSRYR 1213

  Fly  5163 ---EKLDENDKKQKEDG-----ATNKSQKAEAA-----DVVP-EKISE--------EKVAEIKTP 5205
               ..|..|.....::|     |.|.:.|.|.|     .|.| .::||        |:||..:..
Zfish  1214 ISDGALTLNQVALTDEGIYVCRAVNIAGKEETAIQLHVQVPPVVEVSEPPFNSPLQERVANQQIA 1278

  Fly  5206 EPMDSKAKSKP------DGLPADEKSHGAKVSE--------SV-PVKN------------EAEKT 5243
            .|..:|...:|      :|........|..:.|        || |:.|            ..||.
Zfish  1279 FPCPAKGTPEPVIKWFRNGHELTGNEPGVSILEDGTLLILASVSPLDNGEYTCMAVNDAGTTEKK 1343

  Fly  5244 DQLSAK-KPTVLDEDL------VVPKRKPYLAEQTADSISLQTYKSMDSEYKDRKESRSAKRKPT 5301
            .||... .|.:.|..|      |:.:....:.:.|...:.:.|:      |||..|.     .|:
Zfish  1344 YQLKVNVPPDIRDNGLLSNVSVVINQPTNLVCDVTGTPVPVITW------YKDGVEV-----VPS 1397

  Fly  5302 VDIQLTNR-------------------------------------------NTASGSDLK----- 5318
            .|:|:..:                                           .|....||.
Zfish  1398 SDVQILQKGKTLKLLKAAVQDAGRYICKAINIAGSRERDFYLDVLVPPTIIGTVGSRDLSAVLNQ 1462

  Fly  5319 ---LTCGLSGHEM-NVQWFKDNCPIENGAKYRRTLNDGLSCLEIKSAELGDSGIYRCIASNQNGE 5379
               |.|.:.|... .:||:||..|:..|......||.|.. |:||||.|||...|:|.|:|..|:
Zfish  1463 EIVLECKVKGDPFPTIQWYKDRKPVFLGDPNIEVLNRGQQ-LKIKSARLGDQARYQCSATNAAGK 1526

  Fly  5380 VETSCLVTIYEAPSSKFGTPPIFTRNI-RDAYHSQGNQLTLECKVSGSPKPHIYWQRDNTLLPIE 5443
            ......::|:..||.|.|       |: .:.....||.:||||:|.|.|.|.:.|.::..:: :.
Zfish  1527 QSKDFNLSIFVPPSIKGG-------NVSSEVTVLLGNLVTLECEVRGVPLPAVTWYKNGEVI-LS 1583

  Fly  5444 GTKYQYEEQSDGIKLLTINNFGSNDSGLYTCYAESENGQMKISKFVQASDYVRERIA-------- 5500
            ..:.||.::...:|:|...   .:|:|.|||...|..|..:  |.|:...||...|.
Zfish  1584 SRQAQYVDRGQFLKILRAQ---VSDAGQYTCRVTSVAGTAE--KVVELDVYVPPSITAGSDGPTD 1643

  Fly  5501 ---------------------------DKKPID-----KVIQEIKRDESSSAAAND----TAAAK 5529
                                       |..|:.     :|:.:.::.|..:|..:|    ...|.
Zfish  1644 MKVVLNKSLILECEAEGHPPPSLTWLKDGSPVAVRESLRVLDQGRKIEILNALQSDAGRYVCVAT 1708

  Fly  5530 AKAREAKLRLNLETSLKTMTIGS----------GNKAQLICYVTG-IIEDVHWLRN--------D 5575
            :.|.|.:::.::...:..:..|:          .|..:|.||.|| ....:.||::        .
Zfish  1709 SVAGEKEIKYDVSVLVPPVVDGASDTTDATVILNNILELECYATGRPTPTITWLKDGVPVKHGEG 1773

  Fly  5576 ERVTKDARHKIYNINGAISLEIYDARVEDSGHYRCVVKNSRQTVESAGQLSVLDQSTGKLPESF- 5639
            .|:|.:.|.          |.|..|:|.|:..:.||..|.....|...::||      .:|.:.
Zfish  1774 VRITSNGRR----------LVISRAQVSDTALFHCVATNEAGEQEREFKVSV------HVPPAIR 1822

  Fly  5640 SSGIIESYDDQRNEIVLSCQVIG--RPSVSWMRDDHSI-CNNRYRTIEEPGGVRKLVIRNPISSD 5701
            |:|..|........|.|.|.|.|  .||.:|::|...: ....:..:|..|  |.|.|:.....|
Zfish  1823 STGPAERSVVLHTSISLQCVVSGIPPPSTTWLKDGRPVDTTQEFLKLESAG--RVLHIKKARLED 1885

  Fly  5702 CGIFACYAEHEDRIDSTSITIKAADLKRLINVSQEEIPSIGDHESTPWSRSQSHLSSGSQVNGNG 5766
            .|.:.|.|           |..|.:.::.|.:|..|.|||
Zfish  1886 AGKYTCVA-----------TNAAGEAQQHIRLSVHEPPSI------------------------- 1914

  Fly  5767 ELHRAGDRVLRNVGKGKPLFHTLLHDRTVSEGANLRLVCSVSGDENTHIEWLKNHKPLPRSDNRY 5831
              ..||:.:                :.|:..|..::|.|..:|.....:.|.|:.:||..:..
Zfish  1915 --QYAGEML----------------NETILAGFQIQLKCKATGSPLPAVTWYKDGRPLTSAAG-- 1959

  Fly  5832 QTVYLNGEASLEIFAAVADDSGNYTCCATNDFGESLTHAQLRVYKNFKEAPLPSTFT-------- 5888
            ..:...|.. |||..|...|:|.|.|.|.|..|.:.....|:||       :|.|.:
Zfish  1960 VNILSRGHV-LEIDRAQVSDAGFYKCVAINVAGSTELTYSLQVY-------VPPTISSKGGMVTV 2016

  Fly  5889 ---QPIRDTYSLNENELVLDCRVRGQPRPEIQWIKGTEPIEASEKFKPSDQA-DGYAKLVIVNPT 5949
               .|:|           |:|...|.|.|.:.|:|...|:.:   |....|. .|...|..::..
Zfish  2017 VVNDPVR-----------LECEASGVPVPSLTWLKEGSPVSS---FSDGIQVLSGGRVLSFISAQ 2067

  Fly  5950 EKDSGIYWCVARNEGAENKISHQVDFKGRQHYSLEKTHGFFHRDPNKPHFLLPLGNQTVCNGGTV 6014
            ..|:|.|.|||.|.|            |.||...|.      |....|:.:....|.||..|.:|
Zfish  2068 VSDAGHYTCVAVNAG------------GEQHREYEL------RVYVPPNIMGEEVNNTVLMGQSV 2114

  Fly  6015 AISAEFMETSTPIEVKWLRDRRVVDGPNVKALADRGVYTLTIMNAGPEVEGTYTCRASNAFGRIE 6079
            .:..: .:...|..:.|.:|.|.:......::::.|.: |.|::|..:..|.|||.|:|..|:.|
Zfish  2115 QLHCQ-SDAIPPPALSWRKDGRPLYRKPGLSVSEDGSF-LKIISAQVQDTGRYTCEATNVAGKTE 2177

  Fly  6080 SNVNVDVAVGAEKDERPPLFLSRPD-TEMKIAVGDPFSLSFRIAGDPKPKLTFMKGTKDITQSDR 6143
            .:.|::|.|       ||......: :.:.:..|...:|....:|.|.|.|.:.|...::....|
Zfish  2178 KHYNLNVWV-------PPSIRGSDEVSSLTVIEGGLITLVCESSGIPPPSLIWKKDGSELKGDSR 2235

  Fly  6144 VSKEVSDDYTRFSVQQAQISDSGTYFVVARNNFGTD------RIFVTVTVNPRARSATPTQPRWG 6202
            |  .|.....:..:..|:.:|:.:|..:|.:..|:.      :::|..:::..|:..........
Zfish  2236 V--RVLSGGRQLQISSAEKADASSYTCLASSAAGSAIKEYNLQVYVRPSISSSAQDEETVTRGGD 2298

  Fly  6203 LPLDSYSDTSYFRDPPGCISTEPLVVDSGPTHISLSW---GKPVSA-------NSAPVMAYKVEA 6257
            :.|...:|                    |....::||   |:|:|.       |...::.. :||
Zfish  2299 ITLRCEAD--------------------GVPRPAVSWMKDGRPLSTGRKAQILNEGRLLRI-LEA 2342

  Fly  6258 WVVGHEGGAYWRELGLTPINSFDAFNLKPNVEYHFRVTPKNRYGWGPTVQTSSPLQVGGVECLPE 6322
            .|.  :.|.|    ....||.....:.|.:|..|.                  |..:.|...:||
Zfish  2343 QVA--DTGRY----TCIAINVAGQADRKYDVNVHV------------------PPTIIGQTHMPE 2383

  Fly  6323 FVKILPGQAKALLGSSFTLQCNMRGAPRPQVTWFKDGIQLSSSSERVKIRQIGSTCALTIATVSE 6387
            .:.:       ::.:...|.|...|.|.|.:||.|||..:|:||   .:|.|.....|.:...:.
Zfish  2384 NISV-------VVKNPVVLTCEASGMPPPAITWLKDGQPISTSS---SVRVISGGRGLRLMHAAS 2438

  Fly  6388 LDSGRYTCEATNSKGRV-STFARLQVVSDSRIYEADSRLKEIAHGRNVADVGDSLPIFTMRLRDR 6451
            .|:|||||..:||.|.. ..|....:|..|.:.|.           .|.||         ::::|
Zfish  2439 SDAGRYTCIVSNSAGEERKNFDLYVLVPPSIVNEG-----------TVEDV---------KVKER 2483

  Fly  6452 RVQVTYPVRLTCQIVGYPVPEILWYKDDELIHTDRKHLISAEGQFFTLEIAATTLDDSGTYTCLA 6516
            :..:     |.|::.|.|||||.|.||.:.:.:|.:..:.:.|:|  |:|:|:.:.|:|.|:|||
Zfish  2484 QNAI-----LACEVTGNPVPEITWLKDGQPLASDTRLQVMSNGRF--LQISASQVADTGRYSCLA 2541

  Fly  6517 RNELGSVSCHCTLVVDKGIRAYISP------------DFYVPLDPFYIFREGSEIRLSTKVEAYP 6569
            .|..|..|.|..|.|      .:||            :..|.|:        |...|..:.::||
Zfish  2542 SNSAGDRSRHFNLNV------LVSPTIAGSGPEGSAEEVTVTLN--------SPTSLVCEAQSYP 2592

  Fly  6570 SVGVTWHRNGMRLRPSRRLTATLDSNGYVELIIAEATVRDAGIYVCVASNVVGKVETICRVAVEE 6634
            ...:||.::|.....||.:...   .|...|.|..|...|||.|.|||:|..|  ||:     :.
Zfish  2593 PAIITWLKDGTPFESSRNVRVL---PGGRTLQILNAKEEDAGRYTCVATNEAG--ETL-----KN 2647

  Fly  6635 AENKAVAPQRSLEIPSIKTDDLPYSKEPLFVVKPRSSEAYEGDNVIIFCEVVGDPKPEVVWLRDF 6699
            .|.|...|      |.|..:|:|...     :.|:..:....:.:.:.||....|.|.:||.:|
Zfish  2648 YEVKVFVP------PVINKNDIPGES-----LAPKEVKIKVNNTLTLECEAQAIPTPTLVWYKD- 2700

  Fly  6700 LNPEYYKDAPHFRRIGDGPEYRL-EIPSAKLDFTGTYSVIASNCHGEAKAVISLQIFAKDILNKS 6763
              .:..|...|.....:|   |: :|...::..||.|:.:|:|..||.:         ||.
Zfish  2701 --GQILKADGHLTITANG---RIVQIKHTQVSDTGRYTCVATNIAGEDE---------KDF---- 2747

  Fly  6764 RMDKVHTRHGNIETLPRFVRNLRNLRCCDGDA----------------ISLECHVEADPEPFIIW 6812
                    ..||:..|.|    |..    ||:                |||.|...|.|.|.:.|
Zfish  2748 --------DVNIQVPPSF----RGF----GDSGPGNNGEVKDVILNNPISLYCETNAVPPPVLTW 2796

  Fly  6813 EKDGHVMPSDRDYVMSFDGTKATLSIPRVYPEDEGEYTCVAKNSVGRSLSSACIIV--------- 6868
            .||||::.|: |.|:...|.: .|.|||...:|.|.|||||.|..|.......:.|
Zfish  2797 YKDGHLLTSN-DKVLILPGGR-VLQIPRAQVDDTGRYTCVAVNEAGEDSIQYDVRVLLPPSIRGA 2859

  Fly  6869 --DVPEEKENMLSRQLARPSGLLSAHSTPRSTPRSTPARSFSPL------RL--SYRTSSI---- 6919
              ::|:|...::::.:     ||........||:.:..:...||      ||  :.||..|
Zfish  2860 DGELPDEVTVLVNKTM-----LLECQVDGSPTPKISWVKDSQPLTQDNTHRLLSNGRTLQILNAQ 2919

  Fly  6920 ------------DLSGVAER--------------------------------------------- 6927
                        :|:|.||:
Zfish  2920 VTDTGRYVCVAQNLAGTAEKSFNLHVHVSPTIVGIREENVTVVLNNFVSLNCEATGLPPPTLRWF 2984

  Fly  6928 --RR--SDARNAITAP----------------KFLAIPYNRV----------------------- 6949
              ||  ..:.||:..|                |:..:..|..
Zfish  2985 KDRRPVQASTNALIMPGGRTLQILKAKMSDGGKYSCVAVNPAGEAQKLIYLTVYVPPSIRHNSGD 3049

  Fly  6950 ------VEEGDSVRFQCAISGHPTPWATWDKDGLIVTPTPRIAVKEIDDLRIIEIDEVTFDDAGL 7008
                  |:.|.||..:|..:..|.|..||.|:|..:..|..:.:  :.|.:::::.|....|.|.
Zfish  3050 LPVVLNVQVGKSVMLECESNAVPPPVITWYKNGRPIAETANLRI--LADGQMLQLKETEVSDTGQ 3112

  Fly  7009 YRVTLENDFGRIEATARLDV--------------------------------------------- 7028
            |.....|..|:::....|::
Zfish  3113 YVCKATNVAGQVDKNFHLNIHVPPRLDGPAEERVVETISNPVTFACDATGIPPPSLTWLKNGRVI 3177

  Fly  7029 ------------------IRSSRYSKSPSVRSVRAS---SSRRNAHLYRRIMGPSTAIGGRM--- 7069
                              |..|:.|.|.:...|.::   .:::|.||...:  |...||..:
Zfish  3178 ENSESLEMHILSGGSKLQISRSQLSDSGTYTCVASNVEGKAQKNYHLVIHV--PPNIIGSELPSE 3240

  Fly  7070 ---------ALASGYRGSSVPSVRFYHNDVELEASERVHILLQDSMALLIVDNVTREDEGQYTCI 7125
                     .|.....|:..|.:::..:.:.:..:.:.:|.:....:.|.|..|...|.|:|||:
Zfish  3241 MSVLLNDSVQLVCRAEGTPTPEIQWLKDGMTISRTAQKNIKISPDGSTLTVTAVHTSDSGKYTCV 3305

  Fly  7126 I---SGDHD----------PLITSTTVTFHDSNTEIRRRRAVITERLPEITKSLEGEVIDLCCSI 7177
            .   :|:.|          |||........:..|                       |:|...:|
Zfish  3306 ATNQAGEEDRIFNLNVYVPPLIQGNGPAAKELTT-----------------------VLDSSINI 3347

  Fly  7178 EC----DEPYSYVWLRNGEILPDSDEFNYIDHGNGRLCLRINDAFDIDSGIYSC----------- 7227
            ||    ..|....||:||..||.|.:...:..|.   .|||..|...|.|.|:|
Zfish  3348 ECVASGSPPPQLNWLKNGLPLPVSSQIRLLSAGQ---VLRIARAQVSDGGSYTCVASNRAGVDNR 3409

  Fly  7228 ----QVFTSDIND---STSDSTFDSHSICSLINSGC-SDCSSSGELCVLERDLRGQDEECVQLL- 7283
                ||:.....|   ||.:.|....|..|.|   | :|.:.|..:..|........:..:.||
Zfish  3410 HYTLQVYVPPSLDGAGSTEEVTVVKGSTASFI---CIADGTPSPVIIWLRTGASVSKDAHISLLN 3471

  Fly  7284 -KTPLPVV-----------CASGDEALFYARVFPCDAEADWYLNG---------------QLLAQ 7321
             .:.:.:|           |.:.::|...:|.|.........:||               :||.:
Zfish  3472 QNSTMQIVNVLVNHTGRYTCTAHNQAGDASRHFSLKVLDPPRINGSGVPAEVSVVVNHVLELLCE 3536

  Fly  7322 AD----DSLNMTLESYP----ENGIRLLR------------------------------------ 7342
            ||    .:|....:..|    || |||||
Zfish  3537 ADGIPLPTLTWLKDGRPLPQTEN-IRLLRDGQMLRVASAQVENTGRYTCLASSPAGDDDKEFLVR 3600

  Fly  7343 ------------MRDVTASRSGEICLQVKHPQAEFRRIPTTRTY----TSLLVLPAIRGNSSSSS 7391
                        ::||:..::.::.|:.|.....    |.|.|:    ..|.:.|.:|..||...
Zfish  3601 VHVPPNIAGDRGVQDVSVLQNRQVTLECKSDAVP----PPTLTWLKDDAPLKMSPRVRVLSSGRY 3661

  Fly  7392 LAARSCIL--TRPEDCTAL-IGG----HVRLSVRYEP-------------------------FPG 7424
            |...:.:|  .....|.|. :.|    |.:|||...|                         .|.
Zfish  3662 LQINNAVLGDGAQYSCVASNVAGETRRHFKLSVNVPPTIKDGPQSVSVHINQPVVLECVVNGVPA 3726

  Fly  7425 TKVIWYKACHPIVESSNVTIRTTSQQSTLYITDISADDSGKYTVEVMNDYGVEAAAASVAVEGPP 7489
            .::.|.|. ..|:..:|...: ..:..:|.|......|:|:|.....|..|.|.....:.|..|
Zfish  3727 PRITWRKQ-GSILAGNNPRYK-FGEDGSLRILSAQVTDTGRYLCMATNQAGTERKRVDLQVYVP- 3788

  Fly  7490 EPPSGQPSVSLGPDRVAVAWCGPPYDGGCMITGFIIEMQTIGDENCDED-------SWQQVTRVV 7547
                  ||::.||..:.|.                :.:||  ..:|:..       ||.:.|:.:
Zfish  3789 ------PSIAEGPTNITVT----------------VNVQT--TLSCEATGIPKPSVSWTKNTQAL 3829

  Fly  7548 D--------------SLAYTVKNLQPERQYRFRVRAENIHGRSAPGQASELVQITNTPQRSTSSD 7598
            :              ||.....:::....|...|..|       .||.|..:|:|.....|.:.:
Zfish  3830 NTDQNQNMYRLLSSGSLVVIAPSVEDTALYECVVSNE-------AGQESRAIQLTVHVPPSIADE 3887

  Fly  7599 ASD----RFGQATVSVQSGGD-------FKSRFEIIEELGKGRFGIVYKVQERGQPEQLLAAKV- 7651
            |::    |.....:...:.|.       .|....:.:: |:|     :.:...| |.::.||.:
Zfish  3888 ATELVVSRLSPVVIGCTASGVPHPVLYWSKDGLRLAKD-GEG-----FTILPSG-PLEITAADLS 3945

  Fly  7652 ----IKCIKS-------QDRQKVLEEISIMRALQHPKLLQL---------AASFESPREIVM--- 7693
                ..|:..       :..|..:.|..::::  ||..|.:         ..:..|||..:.
Zfish  3946 HSGRYSCVAKNAAGTAHRHVQLTVHESPVIQS--HPSTLDVILNNHVTLPCRATGSPRPTITWQK 4008

  Fly  7694 --VMEYITGG----------ELFERVVADDFTLTEMDCILFLRQVCDGVAYMHGQSVVHLDLKP- 7745
              :..:.|||          ::.:..|.|..|..   |:   .|...|.|.  |::.:.:.:.|
Zfish  4009 EGINIFTTGGGFTVLPNGGLQISKAKVEDSGTYM---CV---AQNPAGTAL--GKTKLRVQVPPV 4065

  Fly  7746 --ENIMCHTRTSHQIKIIDFGLAQRLDTKAPVRVLFGTPEFIPPEIISYEPIG------FQSDMW 7802
              .:|..:|      ..:|..:..:.:::.     |.||.      :|:...|      .:..:.
Zfish  4066 ITSDIRAYT------VALDVSVTLQCNSEG-----FPTPS------VSWHKDGQLLSESVRQRVL 4113

  Fly  7803 SVGVI--------------CYVL-LSGLSPF-------------MGDTDVETFSNITRADYDYDD 7839
            |.|.:              |.|. ::|.|..             :|:::|....| |:|
Zfish  4114 STGALQIAFAQPGDTGRYTCTVANVAGSSSLDISLTVQIPPSIRVGESEVSVVEN-TQA------ 4171

  Fly  7840 EAFDCVSQEAKDFISQLLVHRKEDRLTAQQCLASKWL---------SQRPDDSLSNNKICTDKLK 7895
             ...||:    |.:.|..:..::|.:......|...:         :.:|:||.|...:.|:.:
Zfish  4172 -LLTCVA----DGVPQPTITWEKDDIPLTDTTAEYTILPTGDLLIDTAQPEDSGSYTCVGTNSM- 4230

  Fly  7896 KFIIRRKWQKTGNAIRALG-----------RMANLSVSRRNSAIAM-GVLSSPRPSI-------- 7940
                       |...|.:.           .:.::::::|...:.: ||...|.|.|
Zfish  4231 -----------GQDSRTISLSIHTHPAFTELLGDVALNKRERLLMVCGVTGIPPPKITWTFNNNI 4284

  Fly  7941 --------SGLGMLTTSAIGSGTSSQMTSLHE--------------------EEDDFSGEMPPVE 7977
                    :|...|....:....|...|.:.|                    :.|..|..:.|:.
Zfish  4285 VPAQYDHYNGHSELVIERVSKDDSGTYTCMAENSVGSIKSLGFVYVKEPPIIDGDVHSNRIEPLG 4349

  Fly  7978 KRTVLKLRDKS---------------QCSER----------------SDSGYSEC--SNCSGAQE 8009
            ...:|....:.               |.|.|                .|:|...|  :|.:|..|
Zfish  4350 GNAILNCEVRGDPLPTIQWSKKGINVQISNRIRQLDNGSLAIYGTVSEDAGNYMCVATNDAGVVE 4414

  Fly  8010 -TLLLSLAKSKLEAIAKASTL----PTVVHDTE---QPVS-LELPTKGEAIMRSDF-----TNTI 8060
             |:.|:|.:|....:....|:    .|||.:.:   :||. :|...:|..::.::.     ..::
Zfish  4415 RTVTLTLQRSPTITVEPVETVVDAGSTVVLNCQAEGEPVPVIEWSRQGRPLLGNEHITALNNGSL 4479

  Fly  8061 KMRKKSLEDSAARE 8074
            ::|....||:|..|
Zfish  4480 RLRSAQKEDTAEYE 4493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Strn-Mlck	NP_001261019.1	IG_like	51..127	CDD:214653
		Ig	<69..>112	CDD:299845
		I-set	137..226	CDD:254352
		I-set	235..314	CDD:254352
		Ig_2	244..314	CDD:290606
		I-set	438..513	CDD:254352
		Ig	454..510	CDD:143165
		I-set	537..626	CDD:254352
		Ig	555..618	CDD:299845
		I-set	636..713	CDD:254352
		Ig	652..712	CDD:143165
		SMC_N	<2190..2854	CDD:280601
		I-set	5300..5388	CDD:254352	31/139 (22%)
		IGc2	5313..5378	CDD:197706	26/73 (36%)
		IG	5412..5482	CDD:214652	21/69 (30%)
		IGc2	5413..5481	CDD:197706	21/67 (31%)
		I-set	5542..5627	CDD:254352	21/103 (20%)
		Ig	5556..5621	CDD:143165	18/73 (25%)
		Ig	5654..5721	CDD:143165	18/69 (26%)
		I-set	5784..5874	CDD:254352	22/89 (25%)
		IGc2	5797..5864	CDD:197706	19/66 (29%)
		I-set	5887..5970	CDD:254352	22/94 (23%)
		Ig	5902..5966	CDD:143165	20/64 (31%)
		I-set	5997..6086	CDD:254352	23/88 (26%)
		Ig	6026..6083	CDD:143165	16/56 (29%)
		I-set	6097..6187	CDD:254352	17/96 (18%)
		Ig	6114..6187	CDD:299845	15/78 (19%)
		FN3	6216..6310	CDD:238020	17/103 (17%)
		I-set	6321..6412	CDD:254352	28/91 (31%)
		Ig	6328..6412	CDD:299845	26/84 (31%)
		I-set	6442..6531	CDD:254352	29/88 (33%)
		Ig	6459..6528	CDD:143165	27/68 (40%)
		I-set	6541..6632	CDD:254352	27/102 (26%)
		IGc2	6555..6622	CDD:197706	21/66 (32%)
		I-set	6662..6754	CDD:254352	20/92 (22%)
		Ig	6679..6751	CDD:143165	19/72 (26%)
		I-set	6779..6868	CDD:254352	34/104 (33%)
		IGc2	6793..6858	CDD:197706	30/80 (38%)
		Ig	6938..7022	CDD:299845	22/128 (17%)
		I-set	6939..7028	CDD:254352	23/133 (17%)
		IG	7075..7140	CDD:214652	16/77 (21%)
		Ig	7075..7140	CDD:143165	16/77 (21%)
		IG	7167..7239	CDD:214652	26/93 (28%)
		Ig	7173..7239	CDD:143165	24/87 (28%)
		Ig	7392..7475	CDD:299845	21/114 (18%)
		IG	7406..7475	CDD:214652	18/98 (18%)
		FN3	7489..7588	CDD:238020	20/119 (17%)
		S_TKc	7620..7876	CDD:214567	52/328 (16%)
		STKc_MLCK	7626..7876	CDD:271005	52/322 (16%)
hmcn1	XP_005160777.1	VWA_2	36..206	CDD:290253
		IG_like	443..510	CDD:214653
		I-set	514..600	CDD:254352
		ig	522..596	CDD:278476
		I-set	604..688	CDD:254352
		Ig	618..689	CDD:299845
		I-set	694..781	CDD:254352
		IGc2	708..771	CDD:197706
		I-set	785..876	CDD:254352
		Ig	789..876	CDD:299845
		IG	888..969	CDD:214652
		IGc2	895..959	CDD:197706
		I-set	973..1060	CDD:254352	4/14 (29%)
		Ig	990..1059	CDD:299845	4/13 (31%)
		IG	1084..1162	CDD:214652	21/95 (22%)
		Ig	1092..1159	CDD:143165	19/84 (23%)
		I-set	1166..1251	CDD:254352	17/86 (20%)
		IGc2	1179..1241	CDD:197706	10/61 (16%)
		I-set	1251..1348	CDD:254352	21/96 (22%)
		Ig	1254..1348	CDD:299845	20/93 (22%)
		I-set	1360..1441	CDD:254352	10/91 (11%)
		IGc2	1367..1431	CDD:197706	9/74 (12%)
		I-set	1450..1535	CDD:254352	28/85 (33%)
		IGc2	1461..1525	CDD:197706	24/64 (38%)
		IG_like	1547..1628	CDD:214653	24/86 (28%)
		Ig	1558..1625	CDD:143165	21/72 (29%)
		I-set	1641..1722	CDD:254352	9/80 (11%)
		Ig	1641..1718	CDD:299845	9/76 (12%)
		Ig	1725..1817	CDD:299845	23/107 (21%)
		IG	1738..1815	CDD:214652	20/86 (23%)
		Ig	1818..1908	CDD:299845	25/102 (25%)
		IG	1826..1908	CDD:214652	22/94 (23%)
		IG	1922..2001	CDD:214652	22/81 (27%)
		Ig	1927..2001	CDD:299845	21/76 (28%)
		IG	2014..2093	CDD:214652	26/110 (24%)
		IGc2	2019..2083	CDD:197706	22/89 (25%)
		Ig	2096..2186	CDD:299845	24/91 (26%)
		IG_like	2107..2184	CDD:214653	21/78 (27%)
		Ig	2187..2280	CDD:299845	17/94 (18%)
		I-set	2197..2277	CDD:254352	15/81 (19%)
		Ig	2292..2371	CDD:299845	18/105 (17%)
		IG	2292..2369	CDD:214652	18/103 (17%)
		I-set	2373..2463	CDD:254352	29/99 (29%)
		IGc2	2391..2453	CDD:197706	24/64 (38%)
		IG	2476..2556	CDD:214652	31/95 (33%)
		IGc2	2484..2546	CDD:197706	24/68 (35%)
		IG	2572..2652	CDD:214652	27/97 (28%)
		IGc2	2583..2642	CDD:197706	20/61 (33%)
		I-set	2670..2751	CDD:254352	22/107 (21%)
		IGc2	2678..2741	CDD:197706	17/68 (25%)
		IG	2774..2850	CDD:214652	29/77 (38%)
		IGc2	2777..2840	CDD:197706	28/64 (44%)
		I-set	2864..2945	CDD:254352	17/85 (20%)
		Ig	2864..2938	CDD:299845	15/78 (19%)
		Ig	2949..3039	CDD:299845	7/89 (8%)
		IG_like	2957..3037	CDD:214653	7/79 (9%)
		I-set	3051..3132	CDD:254352	20/82 (24%)
		IGc2	3059..3122	CDD:197706	17/64 (27%)
		I-set	3154..3226	CDD:254352	8/71 (11%)
		Ig	3154..3223	CDD:143165	6/68 (9%)
		Ig	3229..3323	CDD:299845	17/93 (18%)
		I-set	3238..3321	CDD:254352	14/82 (17%)
		IG	3335..3415	CDD:214652	23/105 (22%)
		Ig	3343..3415	CDD:299845	20/74 (27%)
Ig	3418..3508	CDD:299845	18/92 (20%)
IG	3428..3508	CDD:214652	15/82 (18%)
IG	3520..3601	CDD:214652	13/81 (16%)
Ig	<3533..3603	CDD:299845	13/70 (19%)
I-set	3614..3694	CDD:254352	19/83 (23%)
IGc2	3620..3684	CDD:197706	14/67 (21%)
Ig	3697..3787	CDD:299845	15/91 (16%)
IG_like	3704..3785	CDD:214653	13/82 (16%)
Ig	3788..3878	CDD:299845	21/121 (17%)
I-set	3789..3878	CDD:254352	20/113 (18%)
IG_like	3891..3969	CDD:214653	11/84 (13%)
Ig	3899..3968	CDD:299845	10/75 (13%)
IG_like	3979..4060	CDD:214653	16/88 (18%)
Ig	3990..4052	CDD:299845	12/67 (18%)
I-set	4064..4150	CDD:254352	15/102 (15%)
IGc2	4080..4140	CDD:197706	9/70 (13%)
Ig	4161..4241	CDD:299845	17/103 (17%)
IG_like	4161..4241	CDD:214653	17/103 (17%)
I-set	4245..4324	CDD:254352	11/78 (14%)
IGc2	4260..4320	CDD:197706	10/59 (17%)
Ig	4352..4420	CDD:299845	11/67 (16%)
I-set	4425..4511	CDD:254352	13/69 (19%)
Ig	4439..4512	CDD:299845	12/55 (22%)
TSP1	4518..4569	CDD:214559
TSP1	4583..4626	CDD:214559
TSP1	4631..4683	CDD:214559
TSP1	4688..4740	CDD:214559
TSP1	4745..4797	CDD:214559
TSP1	4802..4854	CDD:214559
nidG2	4855..5070	CDD:238158
EGF_CA	5091..5130	CDD:214542
EGF_CA	5131..5174	CDD:284955
EGF_CA	5176..5213	CDD:214542
EGF_CA	5214..5251	CDD:214542
EGF_CA	5256..5297	CDD:284955
EGF_CA	5299..5338	CDD:214542
EGF_CA	5420..5459	CDD:214542
EGF_CA	5460..5496	CDD:214542
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I9840
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	387	1.000	Inparanoid score	I1972
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.050