DRSC/TRiP Functional Genomics Resources

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Protein Alignment Strn-Mlck and mylkb

DIOPT Version :10

Sequence 1:NP_001261019.1 Gene:Strn-Mlck / 36753 FlyBaseID:FBgn0265045 Length:8255 Species:Drosophila melanogaster
Sequence 2:XP_009300538.1 Gene:mylkb / 492576 ZFINID:ZDB-GENE-041111-150 Length:966 Species:Danio rerio


Alignment Length:837 Identity:265/837 - (31%)
Similarity:401/837 - (47%) Gaps:175/837 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly  7154 VITERLPEITKSLEGEVIDLCCSIECDEPYSYVWLRNGEILPDSDEFNYIDHGNGRLCLRINDAF 7218
            |..:.|.:|| .::||.:.|.|.:..|...:..|:.:|:.:..| :|..:.|...:..|.|:.|.
Zfish   167 VFKQPLSDIT-VVDGERLRLECQVTSDLQAAITWILDGKTVKPS-KFIVLSHEGEKCSLTIDKAL 229

  Fly  7219 DIDSGIYSCQVFTSDINDSTSDSTFDSHSICSLINSGCSDCSSSGELCVLERDLRGQDEECVQLL 7283
            ..|.|.|:|:             ..::|        |.::||     ||:..|            
Zfish   230 PEDEGRYTCR-------------AENAH--------GKAECS-----CVVTVD------------ 256

  Fly  7284 KTPLPVVCASGDEALFYARVFPCDAEADWYLNGQLLAQADDSLNMTLESYPENGIRLLRMRDVTA 7348
                                .|.|..||                                     
Zfish   257 --------------------DPSDPSAD------------------------------------- 264

  Fly  7349 SRSGEICLQVKHPQAEFRRIPTTRTYTSLLVLPAIRGNSSSSSLAARSCILTRPEDCTALIGGHV 7413
                      |..:......|||.....:...||.....|...      .|..|.|.....|..|
Zfish   265 ----------KKNRKSSSATPTTENEARIKKKPAPTKQGSPPQ------FLHFPGDQKIRAGEKV 313

  Fly  7414 RLSVRYEPFPGTKVIWYKACHPIVE-SSNVTIRTTSQQSTLYITDISADDSGKYTVEVMNDYGVE 7477
            .|...:...|.....|.|...||.. :..::|.||...|.|.|.....|..|.||:|:.|.:|::
Zfish   314 ELLGNFGGSPPITCTWLKFKKPIQPGNGGISIETTENSSQLTIAASDQDHCGCYTLELQNKFGLK 378

  Fly  7478 AAAASVAVEGPPEPPSGQPSVS-LGPDRVAVAWCGPPYDGGCMITGFIIEMQTIGDENCDEDSWQ 7541
            .|:.::.:...|:||:|.|:.| :....:.::|.||.||||.::..:.:|:.     |..:::|.
Zfish   379 QASLNLTIVDKPDPPAGIPAASDIRRSSLTLSWYGPTYDGGSIVQSYNLEIW-----NSVDNTWN 438

  Fly  7542 QVTRVVDSLAYTVKNLQPERQYRFRVRAENIHGRSAPGQASELVQITNTPQRSTSSDASDRFGQA 7606
            .:|. .:|.::.|:||..:|||:|||||.|::|...|...|..:::  ..:..|.....:..|.|
Zfish   439 DLTS-CNSTSFHVQNLLSDRQYKFRVRAVNVYGVGEPSAESGPIEV--GAEEVTEKKEEEEVGAA 500

  Fly  7607 T-------------VSVQSGGDFKSRFEIIEELGKGRFGIVYKVQERGQPEQLLAAKVIKCIKSQ 7658
            .             |.::.....|..::|.:.||.|:||.|:|:.|:.. :::.|.|.||....:
Zfish   501 VSDDDEEKEPEYRDVVIKKDCSVKDFYDIEDRLGTGKFGQVFKLVEKSS-KKVWAGKFIKAFSQK 564

  Fly  7659 DRQKVLEEISIMRALQHPKLLQLAASFESPREIVMVMEYITGGELFERVVADDFTLTEMDCILFL 7723
            :::.|.:||.||.:|.||||:|...:||...::|||||.|:|||||||:|.:||.|||.:.|.::
Zfish   565 EKENVRQEIGIMNSLHHPKLVQCMDAFEGKSDMVMVMEMISGGELFERIVDEDFELTEREVIKYM 629

  Fly  7724 RQVCDGVAYMHGQSVVHLDLKPENIMCHTRTSHQIKIIDFGLAQRLDTKAPVRVLFGTPEFIPPE 7788
            .|:.|||.::|.|.:||||||||||||..:|..:||:||||||:||:....::||||||||:.||
Zfish   630 LQIIDGVQFIHKQGIVHLDLKPENIMCINKTGSKIKLIDFGLARRLEDSGSLKVLFGTPEFVAPE 694

  Fly  7789 IISYEPIGFQSDMWSVGVICYVLLSGLSPFMGDTDVETFSNITRADYDYDDEAFDCVSQEAKDFI 7853
            :|:||.|.:.:||||:|||||:|:|||||||||.|.||.:|:|.|.:|::|||||.:|.:|||||
Zfish   695 VINYEAISYPTDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFEDEAFDEISDQAKDFI 759

  Fly  7854 SQLLVHRKEDRLTAQQCLASKWLSQRPDDSLSNNKICTDKLKKFIIRRKWQKTGNAIRALGRMAN 7918
            |:||......|||..||....||.| ...::...::..:::||:|:||:|||||||:||:.|   
Zfish   760 SRLLKKDMRARLTCAQCFEHSWLKQ-DTKNMEAKQLSKERMKKYILRRRWQKTGNAVRAISR--- 820

  Fly  7919 LSVSRRNSAIAMGVLSSPRPSISGLGMLTTSAIGSGTSSQMTSLHEEEDDFSGEMPP 7975
                                 .|.:|||      .|...:.:|..|||       ||
Zfish   821 ---------------------FSSMGML------GGIGPKKSSPTEEE-------PP 843

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Strn-MlckNP_001261019.1 Ig_3 26..112 CDD:464046
Ig <70..112 CDD:472250
Ig strand E 92..96 CDD:409353
Ig strand F 106..111 CDD:409353
Ig 137..226 CDD:472250
Ig strand B 154..158 CDD:409353
Ig strand C 167..171 CDD:409353
Ig strand E 192..196 CDD:409353
Ig strand F 206..211 CDD:409353
Ig strand G 219..222 CDD:409353
Ig 235..314 CDD:472250
Ig strand B 251..255 CDD:409564
Ig strand C 264..268 CDD:409564
Ig strand E 280..284 CDD:409564
Ig strand F 294..299 CDD:409564
Ig strand G 307..310 CDD:409564
Ig_3 336..414 CDD:464046
Ig 438..513 CDD:472250
Ig strand B 454..458 CDD:409564
Ig strand C 467..471 CDD:409564
Ig strand E 483..487 CDD:409564
Ig strand F 493..498 CDD:409564
Ig strand G 506..509 CDD:409564
Ig 537..628 CDD:472250
Ig strand B 554..558 CDD:409353
Ig strand C 567..571 CDD:409353
Ig strand F 607..612 CDD:409353
Ig strand G 620..623 CDD:409353
Ig 636..713 CDD:472250
Ig strand B 652..656 CDD:409564
Ig strand C 665..669 CDD:409564
Ig strand E 681..685 CDD:409564
Ig strand F 695..700 CDD:409564
Ig strand G 708..711 CDD:409564
SMC_N <2131..2664 CDD:481474
PTZ00121 <2600..3256 CDD:173412
PTZ00121 <3635..4609 CDD:173412
PTZ00121 <4215..5072 CDD:173412
I-set 5300..5388 CDD:400151
Ig strand B 5317..5321 CDD:409353
Ig strand C 5329..5333 CDD:409353
Ig strand E 5354..5358 CDD:409353
Ig strand F 5368..5373 CDD:409353
Ig_3 5399..5477 CDD:464046
Ig 5542..5627 CDD:472250
Ig strand B 5556..5560 CDD:409353
Ig strand C 5568..5572 CDD:409353
Ig strand E 5593..5597 CDD:409353
Ig strand F 5607..5612 CDD:409353
Ig 5654..5721 CDD:409353
Ig strand B 5654..5658 CDD:409353
Ig strand C 5665..5669 CDD:409353
Ig strand E 5690..5694 CDD:409353
Ig strand F 5704..5709 CDD:409353
Ig strand G 5718..5721 CDD:409353
I-set 5784..5874 CDD:400151
Ig strand B 5801..5805 CDD:409353
Ig strand C 5814..5818 CDD:409353
Ig strand E 5840..5844 CDD:409353
Ig strand F 5854..5859 CDD:409353
Ig 5902..5963 CDD:409353
Ig strand B 5902..5906 CDD:409353
Ig strand C 5915..5919 CDD:409353
Ig strand E 5941..5945 CDD:409353
Ig strand F 5955..5960 CDD:409353
Ig 5997..6086 CDD:472250
Ig strand B 6014..6018 CDD:409353
Ig strand C 6028..6032 CDD:409353
Ig strand E 6050..6056 CDD:409353
Ig strand F 6066..6071 CDD:409353
Ig strand G 6079..6082 CDD:409353
Ig 6107..6187 CDD:472250
Ig strand B 6115..6119 CDD:409353
Ig strand C 6128..6132 CDD:409353
Ig strand E 6153..6157 CDD:409353
Ig strand F 6167..6172 CDD:409353
Ig strand G 6180..6183 CDD:409353
FN3 6216..6310 CDD:238020
I-set 6321..6412 CDD:400151
Ig strand B 6339..6343 CDD:409353
Ig strand C 6352..6356 CDD:409353
Ig strand E 6375..6382 CDD:409353
Ig strand F 6392..6397 CDD:409353
Ig strand G 6405..6408 CDD:409353
I-set 6442..6531 CDD:400151
Ig strand B 6459..6463 CDD:409353
Ig strand C 6472..6476 CDD:409353
Ig strand E 6497..6501 CDD:409353
Ig strand F 6511..6516 CDD:409353
Ig strand G 6524..6527 CDD:409353
Ig 6541..6632 CDD:472250
Ig strand B 6559..6563 CDD:409353
Ig strand C 6572..6576 CDD:409353
Ig strand E 6598..6602 CDD:409353
Ig strand F 6612..6617 CDD:409353
Ig strand G 6625..6628 CDD:409353
Ig 6662..6754 CDD:472250
Ig strand B 6679..6683 CDD:409353
Ig strand C 6692..6696 CDD:409353
Ig strand E 6720..6724 CDD:409353
Ig strand F 6734..6739 CDD:409353
I-set 6779..6868 CDD:400151
Ig strand B 6796..6800 CDD:409353
Ig strand C 6809..6813 CDD:409353
Ig strand E 6834..6838 CDD:409353
Ig strand F 6848..6853 CDD:409353
I-set 6939..7028 CDD:400151
Ig strand B 6956..6960 CDD:409353
Ig strand C 6969..6973 CDD:409353
Ig strand E 6993..6998 CDD:409353
Ig strand F 7008..7013 CDD:409353
Ig strand G 7021..7024 CDD:409353
IG_like 7075..7140 CDD:214653
Ig strand C 7082..7086 CDD:409353
Ig strand E 7107..7111 CDD:409353
Ig strand F 7121..7126 CDD:409353
Ig strand G 7135..7138 CDD:409353
Ig 7173..7232 CDD:409353 15/58 (26%)
Ig strand C 7184..7188 CDD:409353 0/3 (0%)
Ig strand E 7210..7214 CDD:409353 1/3 (33%)
Ig strand F 7224..7229 CDD:409353 2/4 (50%)
IG_like 7406..7475 CDD:214653 20/69 (29%)
Ig strand B 7413..7417 CDD:409353 2/3 (67%)
Ig strand C 7426..7430 CDD:409353 0/3 (0%)
Ig strand E 7451..7455 CDD:409353 2/3 (67%)
Ig strand F 7465..7470 CDD:409353 2/4 (50%)
FN3 7489..7588 CDD:238020 33/99 (33%)
STKc_MLCK 7626..7876 CDD:271005 133/249 (53%)
mylkbXP_009300538.1 I-set 166..255 CDD:400151 27/115 (23%)
Ig strand B 183..187 CDD:409570 1/3 (33%)
Ig strand C 196..200 CDD:409570 0/3 (0%)
Ig strand E 218..225 CDD:409570 1/6 (17%)
Ig strand F 235..240 CDD:409570 2/17 (12%)
Ig strand G 248..251 CDD:409570 2/7 (29%)
Ig 295..394 CDD:472250 27/104 (26%)
Ig strand B 313..317 CDD:409353 2/3 (67%)
Ig strand C 326..330 CDD:409353 0/3 (0%)
Ig strand E 352..356 CDD:409353 2/3 (67%)
Ig strand F 366..371 CDD:409353 2/4 (50%)
Ig strand G 379..382 CDD:409353 1/2 (50%)
FN3 390..475 CDD:238020 31/90 (34%)
Protein Kinases, catalytic domain 524..782 CDD:473864 135/258 (52%)
Ig 866..950 CDD:472250
Ig strand B 877..881 CDD:409353
Ig strand C 890..894 CDD:409353
Ig strand E 916..920 CDD:409353
Ig strand F 930..935 CDD:409353
Ig strand G 943..946 CDD:409353
Blue background indicates that the domain is not in the aligned region.

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