DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4aa1 and CYP735A2

DIOPT Version :9

Sequence 1:	NP_611067.2	Gene:	Cyp4aa1 / 36752	FlyBaseID:	FBgn0034053	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_176882.1	Gene:	CYP735A2 / 843031	AraportID:	AT1G67110	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	547	Identity:	130/547 - (23%)
Similarity:	233/547 - (42%)	Gaps:	79/547 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFVEKVLERTTNLELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTD 65
            |.|..||:..  |.:...|||.|:..||..::.|... ::..:....:|||......||.:.::
plant     1 MMVTLVLKYV--LVIVMTLILRVLYDSICCYFLTPRR-IKKFMERQGITGPKPRLLTGNIIDIS- 61

  Fly    66 KDLMRRCAGKAFDL------------------YGSLVRIWVLLFPFFAVLEPEDLQVILSSKKH- 111
            |.|....:.....:                  ||....:|....|...:.|.|.::.:|:  ||
plant    62 KMLSHSASNDCSSIHHNIVPRLLPHYVSWSKQYGKRFIMWNGTEPRLCLTETEMIKELLT--KHN 124

  Fly   112 --TNKVFFYRL-MHNFLGDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDA 173
              |.|.:..:. ...|:|.||:.::|..|.:.|.:..|||..:.|:.:....|:.::.:.|.|..
plant   125 PVTGKSWLQQQGTKGFIGRGLLMANGEAWHHQRHMAAPAFTRDRLKGYAKHMVECTKMMAERLRK 189

  Fly   174 EAVGTEINIAKYVNNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFR-----------QGKIMMPA 227
            | ||.|:.|.:.:.....||::....|....| |:::..:.....|           .|...:|:
plant   190 E-VGEEVEIGEEMRRLTADIISRTEFGSSCDK-GKELFSLLTVLQRLCAQATRHLCFPGSRFLPS 252

  Fly   228 RFTQPWLLLDGIYHWTKMANDELNQ-KKRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEIS 291
            ::                 |.|:.. |..:.....::|..|:........:|....||..::...
plant   253 KY-----------------NREIKSLKTEVERLLMEIIDSRKDSVEIGRSSSYGDDLLGLLLNQM 300

  Fly   292 ESNRDFTEEDIVNEAC-TFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTM 355
            :||::.....::.:.| ||...|.::....:.:||.||..||..||....|:..:. ..:..|::
plant   301 DSNKNNLNVQMIMDECKTFFFTGHETTSLLLTWTLMLLAHNPTWQDNVRDEVRQVC-GQDGVPSV 364

  Fly   356 TDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIY-PDP 419
            ..|..:..:...|.|:|||||...|:.|...|:::|....:|.|.:::|...|.|....:: .|.
plant   365 EQLSSLTSLNKVINESLRLYPPATLLPRMAFEDIKLGDLIIPKGLSIWIPVLAIHHSNELWGEDA 429

  Fly   420 EKFQPERFSPEN-SENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIA 483
            .:|.||||:..: :.:||   |:||:||||.|||..||:||.|.|::.|:..:..       .|:
plant   430 NEFNPERFTTRSFASSRH---FMPFAAGPRNCIGQTFAMMEAKIILAMLVSKFSF-------AIS 484

  Fly   484 ATFR------ITLRASGGLWVRLKERD 504
            ..:|      :|::...|:.:.||..|
plant   485 ENYRHAPIVVLTIKPKYGVQLVLKPLD 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4aa1	NP_611067.2	p450	50..475	CDD:278495	110/461 (24%)
CYP735A2	NP_176882.1	PLN02290	2..511	CDD:215164	128/544 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910